Cytotoxic Evaluations of Iranian Conifers on Cancer Ells

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Cytotoxic Evaluations of Iranian Conifers on Cancer Ells Publisher

Emami SA¹ ; Sadeghialiabadi H¹ ; Saeidi M² ; Jafarian A³

Source: Pharmaceutical Biology Published:2005

Abstract

In this study, branchlets, fruit, or bark of Taxus baccata L. as well as branchlets or fruits of two other species of Iranian conifers, namely, Platycladus orientalis France and Cupressus sempervirens L. var. horizentalis (Mill) Gunde were collected, identified, and the cytotoxic effects of hydroalcoholic extracts on three human tumor cell lines were determined. Different concentrations of extracts were added to cultured cells and incubated for 72 h. Cell survival was evaluated using the MTT assay. Extracts from bark of female Taxus baccata showed inhibitory activities against Hela cells. The extracts of the branchlets of male and female T. baccata as well as obtained extract from fruits of P. orientalis showed inhibitory activities against MDA-MB-468 cells, whereas the extracts of branchlets of female T. baccata showed inhibitory activities against KB cells. In conclusion, obtained extract from bark of T. baccata showed comparable cytotoxic effect to doxorubicin against Hela cells. © 2005 Taylor & Francis Ltd.

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Style	Citing Format
MLA	Emami SA, et al.. "Cytotoxic Evaluations of Iranian Conifers on Cancer Ells." Pharmaceutical Biology, vol. 43, no. 4, 2005, pp. 299-304.
APA	Emami SA, Sadeghialiabadi H, Saeidi M, Jafarian A (2005). Cytotoxic Evaluations of Iranian Conifers on Cancer Ells. Pharmaceutical Biology, 43(4), 299-304.
Chicago	Emami SA, Sadeghialiabadi H, Saeidi M, Jafarian A. "Cytotoxic Evaluations of Iranian Conifers on Cancer Ells." Pharmaceutical Biology 43, no. 4 (2005): 299-304.
Harvard	Emami SA et al. (2005) 'Cytotoxic Evaluations of Iranian Conifers on Cancer Ells', Pharmaceutical Biology, 43(4), pp. 299-304.
Vancouver	Emami SA, Sadeghialiabadi H, Saeidi M, Jafarian A. Cytotoxic Evaluations of Iranian Conifers on Cancer Ells. Pharmaceutical Biology. 2005;43(4):299-304.
BibTex	@article{ author = {Emami SA and Sadeghialiabadi H and Saeidi M and Jafarian A}, title = {Cytotoxic Evaluations of Iranian Conifers on Cancer Ells}, journal = {Pharmaceutical Biology}, volume = {43}, number = {4}, pages = {299-304}, year = {2005} }
RIS	TY - JOUR AU - Emami SA AU - Sadeghialiabadi H AU - Saeidi M AU - Jafarian A TI - Cytotoxic Evaluations of Iranian Conifers on Cancer Ells JO - Pharmaceutical Biology VL - 43 IS - 4 SP - 299 EP - 304 PY - 2005 ER -

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