Isfahan University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
The Effect of Premediction Oral Naproxen on Post Operative Pain in Diagnostic Laparoscopy Publisher



Shahraki AD1, 5 ; Akhtar JH2 ; Talakob R3 ; Moazam E4
Authors
Show Affiliations
Authors Affiliations
  1. 1. Department of Obstetrics and Gynecology, Al Zahra General Hospital, Isfahan University of Medical Sciences, Isfahan, Iran
  2. 2. Isfahan University of Medical Sciences, Isfahan, Iran
  3. 3. Department of Anaesthesiology, Al Zahra General Hospital, Isfahan University of Medical Sciences, Isfahan, Iran
  4. 4. Department of Community Medicines, Isfahan University of Medical Sciences, Isfahan, Iran
  5. 5. Near Day Laboratory, Isfahan 8173714551, House No. 130, Tohid Street, Iran

Source: Journal of Medical Sciences Published:2009


Abstract

The goal of this study is to investigate the effect of preoperative Naproxen on prevention of postoperative pain and analgesic consumption in females undergoing diagnostic laparoscopy. This is a randomized, double-blinded clinical trial. Qne hundred females (ASA I aqd II, aged 16-45 years old) scheduled for elective diagnostic laparoscopy under general anesthesia were selected by using a computer generated random list patients and were allocated into two equal groups. The patients received either 1 g Naproxen orally or a placebo tablet 90 min prior to anesthesia. Pain scores were significantly lower in Naproxen group compared with the placebo group, during the first 6 h postoperatively. There was also a significant difference between two groups in the analgesic consumption during 24 h after operation (p = 0.004). Preoperative oral Naproxen in diagnostic laparoscopy is effective for post operative pain relief and reduction of analgesic consumption.
Related Docs
View other Related Docs
1. Dose Ranging Effects of Pregabalin on Pain in Patients Undergoing Laparoscopic Hysterectomy: A Randomized, Double Blinded, Placebo Controlled, Clinical Trial, Journal of Clinical Anesthesia (2017)
2. Preemptive Analgesia With Ibuprofen and Acetaminophen in Pediatric Lower Abdominal Surgery, Journal of Research in Medical Sciences (2005)
3. The Effect of Subcutaneous Injection of Metoclopramide, Pethidine, and Ketamine on Postoperative Pain After Inguinal Hernia Repair Under General Anesthesia, Journal of Isfahan Medical School (2020)
4. Pre-Emptive Comparative Study of the Effect of Intravenous Apotel® and Ketorolac on Pain After Laparoscopic Cholecystectomy Surgery Under General Anesthesia: Triple-Blinded Clinical Trial; [و کتورولاک وریدی بر درد پس از جراحی کوله )® بررسی مقایسه ای پره امپتیو تأثیر پاراستامول )آپوتل سیستکتومی لاپاروسکوپی تحت بیهوشی عمومی: کارآزمایی بالینی سه سوکور], Journal of Isfahan Medical School (2024)
5. The Effect of Adding Metoclopramide to Subcutaneous Lidocaine on Postoperative Pain After Lower Abdominal Surgery With General Anesthesia, Journal of Isfahan Medical School (2011)
6. The Preventive Effect of Intramuscular Ketamine and Methadone on Postoperative Pain After Laparoscopic Cholecystectomy, Journal of Isfahan Medical School (2017)
7. The Effect of Intravenous Dexamethasone on Pain, Nausea and Vomiting After Laparoscopic Ovarian Surgery; [تاثير دگسامتازون وريذی بر درد و تهوع و استفراغ پس از عمل جراحی الپاراسکوپيک تخمذان], Tehran University Medical Journal (2023)
8. The Comparison of Preemptive Effects of Propofol, Remifentanil and Ketamine on Post-Operative Pain Scores and Analgesic Requirements in Elective Lower Abdominal Surgery Under General Anesthesia: A Randomized, Double-Blinded Study, Journal of Research in Medical Sciences (2013)
Experts (# of related papers)
View all Related Experts
Azim Honarmand (19)
Gholamreza Khalili (17)
Other Related Docs
9. Effect of Preemptive and Preventive Acetaminophen on Postoperative Pain Score: A Randomized, Double-Blind Trial of Patients Undergoing Lower Extremity Surgery, Journal of Clinical Anesthesia (2013)
10. Premedication With Oral Dextromethorphan Reduces Intra-Operative Morphine Requirement, Journal of Research in Medical Sciences (2005)
11. Comparison of the Effects of Intravenous or Subcutaneous Administration of Metoclopramide on Pain and Nausea After Lower Abdominal Surgery, Journal of Isfahan Medical School (2021)
12. The Effect of Adductor Canal Block on Hemodynamic Variables and Pain After Total Knee Arthroplasty Under Spinal Anesthesia in Comparison With Control Group, Journal of Isfahan Medical School (2017)
13. The Effect of Orally Administered Ketamine on Requirement for Anesthetics and Postoperative Pain in Mandibular Molar Teeth With Irreversible Pulpitis., Journal of oral science (2011)
14. Comparison of the Preemptive Effect of Intravenous Paracetamol and Ketorolac on Prevention of Postoperative Pain in Patients Undergoing Abdominal Surgery, Journal of Isfahan Medical School (2017)
15. The Effects of Two Different Oral Doses of Doxepin on Postoperative Pain in Lower Limb Orthopedic Surgery Patients Compared to a Control Group, Journal of Isfahan Medical School (2012)
16. Effect of Intravenous Infusion of Lidocaine on Pain Reduction After Cesarean Section Under General Anesthesia, Journal of Cellular and Molecular Anesthesia (2018)
17. Effects of Adding Two Different Doses of Intrathecal Magnesium Sulfate to Bupivacaine in Laminectomy Surgeries Under Spinal Anesthesia, Journal of Isfahan Medical School (2017)
18. Ketamine Administration Makes Patients and Physicians Satisfied During Gastro-Enteric Endoscopies, Journal of Research in Medical Sciences (2015)
19. The Effect of Early Ambulation on the Incidence of Neurological Complication After Spinal Anesthesia With Lidocaine, Journal of Research in Medical Sciences (2015)
20. Investigating the Effect of Two Doses of Acetazolamide, As a Precursor for Relief of Referral Pain, After Laparoscopic Cholecystectomy With Carbon Dioxide Gas, and Comparing It With Control Group, Journal of Isfahan Medical School (2018)
21. Comparing the Effects of Ketamine Alone and in Combination With Metoclopramide on Postoperative Pain, Journal of Isfahan Medical School (2013)
22. Comparing the Effect of Lidocaine-Prilocaine Cream and Infiltrative Lidocaine on Overall Pain Perception During Thoracentesis and Abdominocentesis: A Randomized Clinical Trial, Anesthesiology and Pain Medicine (2020)
23. Comparison of Low-Dose Naloxone With Ondansetron for Prevention of Sufentanil-Postoperative/Postdischarge Nausea and Vomiting, Archives of Anesthesiology and Critical Care (2024)
24. Frequency of Pain Intensity and Factors Affecting It After Cesarean Section Using Spinal Anesthesia, Archives of Anesthesiology and Critical Care (2025)
25. Postoperative Analgesia After Caesarean Section: Intermittent Intramuscular Versus Subcutaneous Morphine Boluses, Acute Pain (2007)
26. Comparison of Pre-Emptive Effect of Meloxicam and Celecoxcib on Post-Operative Analgesia: A Double-Blind, Randomized Clinical Trial, Middle East Journal of Anesthesiology (2015)
27. Effect of Different Doses of Paracetamol on Postoperative Pain After Gynecologic Laparoscopy, International Journal of Women's Health and Reproduction Sciences (2018)
28. Mini-Dose Bier's Block Vs Systemic Analgesia in Distal Radius Fractures: A Promising Reduction in Emergency Department Throughput Time, Pain Management (2023)
29. Comparison of the Effects of 3 Methods of Intrathecal Bupivacaine, Bupivacaine-Fentanyl, and Bupivacaine-Fentanyl-Magnesium Sulfate on Sensory Motor Blocks and Postoperative Pain in Patients Undergoing Lumbar Disk Herniation Surgery, Journal of Neurosurgical Anesthesiology (2016)
30. Supplementing Epidural Lidocaine With Midazolam: Effect on Sensorymotor Block Level, Acta Anaesthesiologica Taiwanica (2004)
31. Effects of Lidocaine on Reducing the Need for Anesthetic Drugs During Ophthalmologic Surgeries, Journal of Isfahan Medical School (2013)
32. Comparison of Oral Melatonin and Midazolam As Premedication in Children Undergoing General Anesthesia for Dental Treatment, Anesthesiology and Pain Medicine (2018)
33. The Efficacy Comparison of Ibuprofen, Acetaminophen-Codeine, and Placebo Premedication Therapy on the Depth of Anesthesia During Treatment of Inflamed Teeth, Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontology (2006)
34. The Comparison of Spinal Anesthesia With General Anesthesia on the Postoperative Pain Scores and Analgesic Requirements After Elective Lower Abdominal Surgery: A Randomized, Double-Blinded Study, Journal of Research in Medical Sciences (2013)
35. Comparison of the Effects of Preoperative Celecoxib and Gabapentin on Pain, Functional Recovery, and Quality of Life After Total Knee Arthroplasty: A Randomized Controlled Clinical Trial, Journal of Research in Medical Sciences (2023)
36. Evaluation of the Efficacy of the Valsalva Maneuver and Fentanyl Administration for Attenuating Etomidate Injection Pain: A Double-Blind Clinical Trial, Journal of Emergency Practice and Trauma (2024)
37. Comparison of the Sedation Quality of Etomidate, Propofol, and Midazolam in Combination With Fentanyl During Phacoemulsification Cataract Surgery: A Double-Blind, Randomized, Controlled, Clinical Trial, Anesthesiology and Pain Medicine (2019)
38. Effects of Age and Gender on Acute Postoperative Pain After Cataract Surgery Under Topical Anesthesia and Sedation, Journal of Isfahan Medical School (2017)
39. The Effects of Intraarticular Opioids in Pain Relief After Arthroscopic Menisectomy: A Randomized Clinical Trial Study, Pakistan Journal of Medical Sciences (2012)
40. Comparing the Effectiveness of Intrathecal Injection of Marcaine With Magnesium Sulfate, Neostigmine or Phentanyl on Post-Operative Pain, Urinary Retention, Nausea or Vomiting in Patients Undergoing Spinal Anesthesia for Lumbar Disk Herniation Surgery, Journal of Isfahan Medical School (2016)
41. Comparison of the Preventive Effect of Ketamine, Paracetamol and Metoclopramide on Postoperative Pain Intensity in General Anesthesia: A Double-Blind Clinical Trial, Scientific Journal of Kurdistan University of Medical Sciences (2019)
42. Topical Lidocaine Plus Diclofenac As a Local Anesthetic Agent in Central Venous Catheterization; a Randomized Controlled Clinical Trial, Archives of Academic Emergency Medicine (2021)
43. Comparison of Intravenous and Epidural Patient-Controlled Analgesia After Knee and Hip Arthroplasty, Journal of Isfahan Medical School (2012)
44. Cotimparave Evaluation of Oral Alprazolam, As Premedication, on Controlling Blood Pressure in Hypertensive Patients During Surgery, Journal of Isfahan Medical School (2015)
45. Comparison Study of Preemptive Effect of Intratechal Fentanyl With Intravenous Ondansetron, Dexamethasone, and Dexamethasone Plus Ondansetron on Shivering During Surgeries Under Spinal Anesthesia With Bupivacaine, Journal of Isfahan Medical School (2017)
46. Midazolam Versus Ketamine in the Management of Emergence Agitation in Children Undergoing Lower Abdominal and Limb Surgeries, Tehran University Medical Journal (2012)
47. Investigating the Effect of Melissa Officinalis on After-Pains: A Randomized Single-Blind Clinical Trial, Journal of Caring Sciences (2019)
48. A Comparison of the Effects of Fentanyl and Remifentanil on Nausea, Vomiting, and Pain After Cesarean Section, Iranian Journal of Medical Sciences (2011)
49. Comparison of Parenteral Promethazine Versus Midazolam Effect As a Preoperative Medication on Postoperative Nausea and Vomiting After Appendectomy, Caspian Journal of Internal Medicine (2011)
50. Comparison the Efficacy of Pre-Emptive Oral Celecoxib With Acetaminophen in Controlling Post-Operative Pain and Nausea After Lower Limb Surgery Under General Anesthesia, Journal of Cellular and Molecular Anesthesia (2016)