Isfahan University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
Diet Macronutrients Composition in Nonalcoholic Fatty Liver Disease: A Review on the Related Documents Publisher



Hashemi Kani A1, 2 ; Alavian SM3 ; Haghighatdoost F1, 2 ; Azadbakht L1, 2
Authors
Show Affiliations
Authors Affiliations
  1. 1. Food Security Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
  2. 2. Department of Community Nutrition, School of Nutrition and Food Science, Isfahan University of Medical Sciences, Isfahan, Iran
  3. 3. Middle East Liver Diseases Center (MELD), Tehran, Iran

Source: Hepatitis Monthly Published:2014


Abstract

Context: Non-alcoholic fatty liver disease (NAFLD) is a growing health problem in both developed and developing countries. Metabolic abnormalities, specially insulin resistance and hyperglycemia are highly correlated with NAFLD. Lifestyle modifications including physical activity and promoting nutrient intakes are critical in prevention and treatment of NAFLD. Hence, in this article we aimed to review the evidence regarding the effects of various macronutrients on fat accumulation in hepatic cells as well as the level of liver enzymes. Evidence Acquisitions: The relevant English and non-English published papers were searched using online databases of PubMed, ISI Web of Science, SCOPUS, Science Direct and EMBASE from January 2000 to January 2013. We summarized the findings of 40 relevant studies in this review. Results: Although a hypocaloric diet could prevent the progression of fat accumulation in liver, the diet composition is another aspect which should be considered in diet therapy of patients with NAFLD. Conclusions: Several studies assessed the effects of dietary composition on fat storage in liver; however, their findings are inconsistent. Most studies focused on the quantity of carbohydrate and dietary fat; whilst there is very limited information regarding the role of protein intake. © 2014, Kowsar Corp.
Related Docs
View other Related Docs
1. Dietary Quality Indices and Biochemical Parameters Among Patients With Non Alcoholic Fatty Liver Disease (Nafld), Hepatitis Monthly (2013)
2. Metabolic Syndrome and Nonalcoholic Fatty Liver Disease: Nutritional Approach for Prevention, Journal of Isfahan Medical School (2013)
3. The Effects of Low Carbohydrate Diets on Liver Function Tests in Nonalcoholic Fatty Liver Disease: A Systematic Review and Meta-Analysis of Clinical Trials, Journal of Research in Medical Sciences (2016)
4. Adherence to Low Carbohydrate Diets and Non-Alcoholic Fatty Liver Disease: A Case Control Study, BMC Nutrition (2022)
5. Effects of a Novel Therapeutic Diet on Liver Enzymes and Coagulating Factors in Patients With Non-Alcoholic Fatty Liver Disease: A Parallel Randomized Trial, Nutrition (2014)
6. The Effect of a Mediterranean Diet on Metabolic Parameters in Patients With Non-Alcoholic Fatty Liver Disease: A Systematic Review of Randomized Controlled Trials, Clinical Nutrition ESPEN (2020)
7. Intake of Nutrients, Fiber, and Sugar in Patients With Nonalcoholic Fatty Liver Disease in Comparison to Healthy Individuals, International Journal of Preventive Medicine (2016)
8. Probiotics As a Novel Treatment for Non-Alcoholic Fatty Liver Disease; a Systematic Review on the Current Evidences, Hepatitis Monthly (2013)
Experts (# of related papers)
View all Related Experts
Roya Kelishadi (23)
Gholamreza Askari (23)
Other Related Docs
9. The Effect of Symbiotic Supplementation on Liver Enzymes, C‑Reactive Protein and Ultrasound Findings in Patients With Non‑Alcoholic Fatty Liver Disease: A Clinical Trial, International Journal of Preventive Medicine (2016)
10. Dietary Patterns and Risk of Non-Alcoholic Fatty Liver Disease, BMC Gastroenterology (2021)
11. The Role of Omega-3 Fatty Acids on the Prevention and Treatment of Non-Alcoholic Fatty Liver Disease: A Review of Published Papers, Journal of Isfahan Medical School (2014)
12. The Association Between the Dietary Inflammatory Index (Dii) and Some Serum Oxidative Stress Markers in Non-Alcoholic Fatty Liver Disease: Case-Control, International Journal of Preventive Medicine (2022)
13. Determination of Frequency of Diabetes and Pre-Diabetes in Patients With Nonalcoholic Fatty Liver Disease and Comparison With a Control Group, Journal of Isfahan Medical School (2016)
14. Sesame Oil Ameliorates Alanine Aminotransferase, Aspartate Aminotransferase, and Fatty Liver Grade in Women With Nonalcoholic Fatty Liver Disease Undergoing Low-Calorie Diet: A Randomized Double-Blind Controlled Trial, International journal of clinical practice (2022)
15. Association of Conjugated Linoleic Acid Consumption and Liver Enzymes in Human Studies: A Systematic Review and Meta-Analysis of Randomized Controlled Clinical Trials, Nutrition (2016)
16. Effects of a Low-Calorie, Low-Carbohydrate Soy Containing Diet on Systemic Inflammation Among Patients With Nonalcoholic Fatty Liver Disease: A Parallel Randomized Clinical Trial, Hormone and Metabolic Research (2017)
17. Vitamin D Supplementation and Non-Alcoholic Fatty Liver Disease: A Critical and Systematic Review of Clinical Trials, Critical Reviews in Food Science and Nutrition (2019)
18. Predictive Factors of Steatosis and Non-Alcoholic Steatohepatitis in Morbidly Obese Patients Undergoing Bariatric Surgery, Hepatitis Monthly (2017)
19. Relationship Between Major Dietary Patterns and Metabolic Syndrome Among Individuals With Impaired Glucose Tolerance, Nutrition (2010)
20. The Relationship Between Dietary Antioxidant Intake and Physical Activity Rate With Nonalcoholic Fatty Liver Disease (Nafld): A Case – Control Study, Clinical Nutrition ESPEN (2019)
21. Vitamin E + Ursodeoxycholic Acid (Udca) Versus Vitamin E for the Treatment of Non-Alcoholic Steatohepatitis (Nash), Journal of Isfahan Medical School (2010)
22. Effect of a Moderately Carbohydrate-Restricted Diet on Liver Enzymes, Steatosis and Fibrosis in Normal-Weight Individuals With Non-Alcoholic Fatty Liver Disease: Study Protocol for a Parallel Randomised Controlled Clinical Trial, BMJ Open (2023)
23. The Association Between Major Dietary Patterns With the Risk of Non-Alcoholic Fatty Liver Disease, Oxidative Stress and Metabolic Parameters: A Case–Control Study, Journal of Diabetes and Metabolic Disorders (2022)
24. Direct Association Between High Fat Dietary Pattern and Risk of Being in the Higher Stages of Chronic Kidney Disease, International Journal for Vitamin and Nutrition Research (2019)
25. The Effect of Synbiotic Supplementation on Body Composition and Lipid Profile in Patients With Nafld: A Randomized, Double Blind, Placebo-Controlled Clinical Trial Study, Iranian Red Crescent Medical Journal (2017)
26. The Effects of Fasting Diets on Nonalcoholic Fatty Liver Disease, Nutrition Reviews (2023)
27. Effects of Lacto-Ovo-Vegetarian Diet Vs. Standard-Weight-Loss Diet on Obese and Overweight Adults With Non-Alcoholic Fatty Liver Disease: A Randomised Clinical Trial, Archives of Physiology and Biochemistry (2023)
28. The Effects of High Fructose Fruits and Honey on the Serum Level of Metabolic Factors and Nonalcoholic Fatty Liver Disease, Journal of Diabetes and Metabolic Disorders (2021)
29. The Association of the Healthy Food Diversity Index With the Risk of Non-Alcoholic Fatty Liver Disease Among the Adult Population, Clinical Nutrition ESPEN (2024)
30. A Narrative Review on the Role of Hesperidin on Metabolic Parameters, Liver Enzymes, and Inflammatory Markers in Nonalcoholic Fatty Liver Disease, Food Science and Nutrition (2023)
31. Dietary Diversity Score Is Related to Obesity and Abdominal Adiposity Among Iranian Female Youth, Public Health Nutrition (2011)
32. A Cross-Sectional Study on Food Patterns and Adiposity Among Individuals With Abnormal Glucose Homeostasis, Archives of Iranian Medicine (2012)
33. Quantity and Quality of Carbohydrate Intake in Iran: A Target for Nutritional Intervention, Archives of Iranian Medicine (2012)
34. Doppler Perfusion Index in Adolescents With Nonalcoholic Fatty Liver Disease, Immunopathologia Persa (2021)
35. Identification of Diet-Disease Relations Through Dietary Pattern Approach: A Review, Journal of Research in Medical Sciences (2008)
36. Healthy Eating Index and Cardiovascular Risk Factors Among Iranians, Journal of the American College of Nutrition (2013)
37. Dietary Patterns in Relation to Lipid Profiles Among Iranian Adults, Journal of Cardiovascular and Thoracic Research (2019)
38. Effect of Vitamin D Supplement on Nonalcoholic Fatty Liver: A Systematic Review on Randomized Clinical Trials, Journal of Health System Research (2020)
39. A Comprehensive Insight Into the Effect of Berberine on Nonalcoholic Fatty Liver Disease (Nafld): A Systematic Review, Journal of Food Biochemistry (2023)
40. Sustained Feeding of a Diet High in Fat Resulted in a Decline in the Liver's Insulin-Degrading Enzyme Levels in Association With the Induction of Oxidative and Endoplasmic Reticulum Stress in Adult Male Rats: Evaluation of 4-Phenylbutyric Acid, Heliyon (2024)
41. The Effects of Metformin Administration on Liver Enzymes and Body Composition in Non-Diabetic Patients With Non-Alcoholic Fatty Liver Disease And/Or Non-Alcoholic Steatohepatitis: An Up-To Date Systematic Review and Meta-Analysis of Randomized Controlled Trials, Pharmacological Research (2020)
42. The Effects of Zinc Supplementation on Metabolic Profile and Oxidative Stress in Overweight/Obese Patients With Non-Alcoholic Fatty Liver Disease: A Randomized, Double-Blind, Placebo-Controlled Trial, Journal of Trace Elements in Medicine and Biology (2020)
43. Adherence to Alternative Healthy Eating Index (Ahei-2010) Is Not Associated With Risk of Stroke in Iranian Adults: A Case-Control Study, International Journal for Vitamin and Nutrition Research (2021)
44. The Effects of Sumac (Rhus Coriaria L.) Powder Supplementation in Patients With Non-Alcoholic Fatty Liver Disease: A Randomized Controlled Trial, Complementary Therapies in Clinical Practice (2020)
45. The Association Between Non Soy Legume Consumption and Cardiovascular Risk Factors, Journal of Babol University of Medical Sciences (2015)
46. Association Between Mean Adequacy Ratio As Diet Quality Index and Anthropometric Indices in Children and Adolescents, Mediterranean Journal of Nutrition and Metabolism (2019)
47. Effect of Sour Tea Supplementation on Liver Enzymes, Lipid Profile, Blood Pressure, and Antioxidant Status in Patients With Non-Alcoholic Fatty Liver Disease: A Double-Blind Randomized Controlled Clinical Trial, Phytotherapy Research (2021)
48. Obesity and Air Pollution: Global Risk Factors for Pediatric Non-Alcoholic Fatty Liver Disease, Hepatitis Monthly (2011)
49. The Effect of a Lifestyle Modification Education on Adiposity Measures in Overweight and Obese Nonalcoholic Fatty Liver Disease Patients, International Journal of Preventive Medicine (2017)
50. Effect of a High Protein Weight Loss Diet on Weight, High-Sensitivity C-Reactive Protein, and Cardiovascular Risk Among Overweight and Obese Women: A Parallel Clinical Trial, International Journal of Endocrinology (2013)