Nanosponges: An Overlooked Promising Strategy to Combat Sars-Cov-2

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Nanosponges: An Overlooked Promising Strategy to Combat Sars-Cov-2 Publisher Pubmed

Mostafavi E^{1, 2} ; Iravani S³ ; Varma RS⁴

Source: Drug Discovery Today Published:2022

Abstract

Among explored nanomaterials, nanosponge-based systems have exhibited inhibitory effects for the biological neutralization of, and antiviral delivery against, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). More studies could pave the path for clarification of their biological neutralization mechanisms as well as the assessment of their long-term biocompatibility and biosafety issues before clinical translational studies. In this review, we discuss recent advances pertaining to antiviral delivery and inhibitory effects of nanosponges against SARS-CoV-2, focusing on important challenges and opportunities. Finally, as promising approaches for recapitulating the complex structure of different organs/tissues of the body, we discuss the use of 3D in vitro models to investigate the mechanism of SARS-CoV-2 infection and to find therapeutic targets to better manage and eradicate coronavirus 2019 (COVID-19). © 2022 Elsevier Ltd

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Style	Citing Format
MLA	Mostafavi E, Iravani S, Varma RS. "Nanosponges: An Overlooked Promising Strategy to Combat Sars-Cov-2." Drug Discovery Today, vol. 27, no. 10, 2022, pp. -.
APA	Mostafavi E, Iravani S, Varma RS (2022). Nanosponges: An Overlooked Promising Strategy to Combat Sars-Cov-2. Drug Discovery Today, 27(10), -.
Chicago	Mostafavi E, Iravani S, Varma RS. "Nanosponges: An Overlooked Promising Strategy to Combat Sars-Cov-2." Drug Discovery Today 27, no. 10 (2022): -.
Harvard	Mostafavi E, Iravani S, Varma RS (2022) 'Nanosponges: An Overlooked Promising Strategy to Combat Sars-Cov-2', Drug Discovery Today, 27(10), pp. -.
Vancouver	Mostafavi E, Iravani S, Varma RS. Nanosponges: An Overlooked Promising Strategy to Combat Sars-Cov-2. Drug Discovery Today. 2022;27(10):-.
BibTex	@article{ author = {Mostafavi E and Iravani S and Varma RS}, title = {Nanosponges: An Overlooked Promising Strategy to Combat Sars-Cov-2}, journal = {Drug Discovery Today}, volume = {27}, number = {10}, pages = {-}, year = {2022} }
RIS	TY - JOUR AU - Mostafavi E AU - Iravani S AU - Varma RS TI - Nanosponges: An Overlooked Promising Strategy to Combat Sars-Cov-2 JO - Drug Discovery Today VL - 27 IS - 10 SP - EP - PY - 2022 ER -

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