Cerium Oxide Nanoparticles: A Promising Tool for the Treatment of Fibrosarcoma In-Vivo

Cerium Oxide Nanoparticles: A Promising Tool for the Treatment of Fibrosarcoma In-Vivo Publisher Pubmed

Nourmohammadi E^{1, 2} ; Khoshdelsarkarizi H³ ; Nedaeinia R⁴ ; Darroudi M⁵ ; Kazemi Oskuee R⁶

Show Affiliations

1. Department of Medical Biotechnology and Nanotechnology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
2. Research Center of Advanced Technology in Medicine, Torbat Heydariyeh University of Medical Sciences, Torbat Heydariyeh, Iran
3. Department of Anatomical Sciences and Cell Biology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
4. Isfahan Cardiovascular Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
5. Nuclear Medicine Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
6. Targeted Drug Delivery Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran

Source: Materials Science and Engineering C Published:2020

Abstract

In this study, we used cerium oxide nanoparticles and evaluated their anti-cancer effects in a mouse model of fibrosarcoma. For evaluation of anti-cancer effects of nanoceria, tumor volume measurement, TUNEL (terminal deoxynucleotidyl transferase dUTP nick end labeling) assay, quantitative real-time PCR (qPCR) for Bax and Bcl2 genes, a panel of liver and kidney function tests and hematoxylin-eosin staining were done. Nanoceria dominantly accumulated in the tumor and it could significantly decrease tumor growth and volume in tumor-bearing mice that received nanoceria for four weeks. Cerium oxide nanoparticle showed potential anti-cancer properties against fibrosarcoma. © 2019 Elsevier B.V.

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Style	Citing Format
MLA	Nourmohammadi E, et al.. "Cerium Oxide Nanoparticles: A Promising Tool for the Treatment of Fibrosarcoma In-Vivo." Materials Science and Engineering C, vol. 109, no. , 2020, pp. -.
APA	Nourmohammadi E, Khoshdelsarkarizi H, Nedaeinia R, Darroudi M, Kazemi Oskuee R (2020). Cerium Oxide Nanoparticles: A Promising Tool for the Treatment of Fibrosarcoma In-Vivo. Materials Science and Engineering C, 109(), -.
Chicago	Nourmohammadi E, Khoshdelsarkarizi H, Nedaeinia R, Darroudi M, Kazemi Oskuee R. "Cerium Oxide Nanoparticles: A Promising Tool for the Treatment of Fibrosarcoma In-Vivo." Materials Science and Engineering C 109, no. (2020): -.
Harvard	Nourmohammadi E et al. (2020) 'Cerium Oxide Nanoparticles: A Promising Tool for the Treatment of Fibrosarcoma In-Vivo', Materials Science and Engineering C, 109(), pp. -.
Vancouver	Nourmohammadi E, Khoshdelsarkarizi H, Nedaeinia R, Darroudi M, Kazemi Oskuee R. Cerium Oxide Nanoparticles: A Promising Tool for the Treatment of Fibrosarcoma In-Vivo. Materials Science and Engineering C. 2020;109():-.
BibTex	@article{ author = {Nourmohammadi E and Khoshdelsarkarizi H and Nedaeinia R and Darroudi M and Kazemi Oskuee R}, title = {Cerium Oxide Nanoparticles: A Promising Tool for the Treatment of Fibrosarcoma In-Vivo}, journal = {Materials Science and Engineering C}, volume = {109}, number = {}, pages = {-}, year = {2020} }
RIS	TY - JOUR AU - Nourmohammadi E AU - Khoshdelsarkarizi H AU - Nedaeinia R AU - Darroudi M AU - Kazemi Oskuee R TI - Cerium Oxide Nanoparticles: A Promising Tool for the Treatment of Fibrosarcoma In-Vivo JO - Materials Science and Engineering C VL - 109 IS - SP - EP - PY - 2020 ER -

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