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The Effect of Food Ration Bar Enriched With Β-Alanine, L-Arginine, and Nigella Sativa on Performance and Inflammation Following Intense Military Training: A Double-Blind Randomized Clinical Trial Publisher



Hadi S1, 2 ; Miryan M3 ; Soleimani D4 ; Amani R1 ; Mazaheri Tehrani M5 ; Hadi V2 ; Esmaiil Zali M6 ; Mosalmanzadeh N7 ; Askari G1, 8
Authors
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Authors Affiliations
  1. 1. Department of Community Nutrition, School of Nutrition and Food Sciences, Isfahan University of Medical Sciences, Isfahan, Iran
  2. 2. Department of Health, Science and Research Branch, AJA University of Medical Sciences, Tehran, Iran
  3. 3. Nutrition Research Center, Student Research Committee, Department of Clinical Nutrition, School of Nutrition and Food Sciences, Tabriz University of Medical Sciences, Tabriz, Iran
  4. 4. Nutritional Sciences Department, School of Nutrition Sciences and Food Technology, Kermanshah University of Medical Sciences, Kermanshah, Iran
  5. 5. Department of Food Science and Technology, Faculty of Agriculture, Ferdowsi University of Mashhad, Mashhad, Iran
  6. 6. Department of Management and Health Economy, Faculty of Medicine, AJA University of medical sciences, Tehran, Iran
  7. 7. Department of Nutrition Sciences, Varastegan Institute for Medical Sciences, Mashhad, Iran
  8. 8. Food Security Research Center, Isfahan University of Medical Sciences, Isfahan, Iran

Source: Food Science and Nutrition Published:2021


Abstract

Background: There are growing interests in using dietary supplements to improve athletic performance. This study aimed to evaluate the effect of the food ration bar enriched with β-alanine, L-arginine, and Nigella sativa on athletic performance and inflammation following intense military training. Methods: This double-blind, randomized, controlled clinical trial was conducted on 54 new cadets. Eligible participants were randomly assigned in a 1:1 ratio to receive food ration bars enriched with arginine (2 g/day), β-alanine (2 g/day), and Nigella sativa (2 g/day) or nonenriched food ration bars during a 2-week military training. Aerobic and anaerobic performances were evaluated by the Cooper and RAST tests, respectively. Results: A significant increase in anaerobic powers (min, mean, and max) and a significant reduction in fatigue index were observed in the intervention group as compared to the control group, even after the adjustment for confounding factors. Also, increased levels of hs-CRP and TNF-α following military training were significantly lower in the intervention group as compared to the control group (hs-CRP: 0.55 ± 0.1 versus 2.43 ± 0.1 mg/L; p-value: 0.01; TNF-α: 0.12 ± 0.04 versus 0.62 ± 0.04 pg/ml; p-value: 0.03). No significant changes were observed in VO2 max in both groups. Conclusions: Our results showed that the combination of β-alanine, L-arginine, and Nigella sativa can improve anaerobic performance and reduce inflammation following intense physical activities. Further studies with long-term duration are needed to confirm the cumulative/synergic effects of these ingredients in trained and nontrained subjects. © 2021 The Authors. Food Science & Nutrition published by Wiley Periodicals LLC.
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