Isfahan University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
Adherence to Mediterranean Diet and Its Association With Metabolic Health Status in Overweight and Obese Adolescents Publisher Pubmed



Mohammadi S1 ; Lotfi K2 ; Mirzaei S3 ; Asadi A4 ; Akhlaghi M3 ; Saneei P5
Authors
Show Affiliations
Authors Affiliations
  1. 1. Department of Community Nutrition, School of Nutrition and Food Science, Nutrition and Food Security Research Center, Students' Research Committee, Isfahan University of Medical Sciences, Isfahan, Iran
  2. 2. Department of Community Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran
  3. 3. Department of Community Nutrition, School of Nutrition and Food Science, Shiraz University of Medical Sciences, Shiraz, Iran
  4. 4. Department of Exercise Physiology, School of Physical Education and Sport Sciences, University of Tehran, Tehran, Iran
  5. 5. Department of Community, School of Nutrition and Food Science, Nutrition and Food Security Research Center, Isfahan University of Medical Sciences, Isfahan, Iran

Source: International Journal of Clinical Practice Published:2022


Abstract

Background. Obesity is becoming more prevalent around the world and greatly contributes to chronic disease progression. Previous studies have investigated individual food groups in relation to metabolic health status of adolescents, mainly in Western countries. Limited data are available on the association between dietary patterns and metabolic health in Middle East nations, where childhood overweight/obesity is increasing drastically. Therefore, we investigated the relationship between the Mediterranean diet and metabolic health status among Iranian adolescents. Methods. This cross-sectional study was conducted on 203 overweight/obese adolescents. Dietary intakes were evaluated by a validated food frequency questionnaire. Anthropometric parameters and blood pressure were measured. Fasting blood samples were obtained to determine circulating insulin, glucose, and lipid profile. Two different methods were applied to classify participants as metabolically healthy obese (MHO) or unhealthy obese (MUO): International Diabetes Federation (IDF) criteria and IDF along with insulin resistance (HOMA-IR) criteria. Results. A total of 79 (38.9%) and 67 (33.0%) adolescents were, respectively, categorized as MUO, based on IDF and IDF/HOMA definitions. Considering IDF criteria, higher adherence to the Mediterranean diet was related to lower odds of being MUO, both in the crude (OR: 0.17; 95%CI: 0.08-0.37) and fully adjusted model (OR: 0.33; 95% CI: 0.13-0.84). Excluding each component from the score made the association insignificant, except for two components of meat and dairy products. Based on the IDF/HOMA-IR criteria, there was no significant association between Mediterranean diet score and MUO, after considering all potential confounders (OR: 0.47; 95% CI: 0.17-1.30). Conclusions. We found an inverse association between the Mediterranean diet and odds of MUO among Iranian adolescents, based on IDF criteria. No significant relation was found when MUO was defined based on HOMA-IR/IDF criteria. Further prospective cohort studies are needed to confirm these findings. © 2022 Sobhan Mohammadi et al.
Related Docs
View other Related Docs
1. Association Between Major Dietary Patterns and Metabolic Health Status in Overweight and Obese Adolescents, Nutrition (2022)
2. Association of Dietary Insulin Index and Dietary Insulin Load With Metabolic Health Status in Iranian Overweight and Obese Adolescents, Frontiers in Nutrition (2022)
3. Association of Priori-Defined Dash Dietary Pattern With Metabolic Health Status Among Iranian Adolescents With Overweight and Obesity, Scientific Reports (2024)
4. Association of Legumes and Nuts Consumption With Metabolic Health Status in Iranian Overweight And Obese Adolescents, Scientific Reports (2023)
5. Nutrient Patterns in Relation to Metabolic Health Status in Overweight and Obese Adolescents, Scientific Reports (2023)
6. The Association Between Egg Consumption and Metabolic Health Status in Overweight and Obese Adolescents, Scientific Reports (2023)
7. Ultra-Processed Food Intake in Relation to Metabolic Health Status in Iranian Adolescents With Overweight and Obesity, Nutrition and Metabolism (2024)
8. Total Dietary Fiber Intake Is Inversely Associated With Metabolically Unhealthy Status in Adolescents With Excess Weight, Nutrition Research (2024)
Experts (# of related papers)
View all Related Experts
Roya Kelishadi (290)
Nizal Sarrafzadegan (105)
Other Related Docs
9. The Relationship Between the Mediterranean-Dash Intervention for Neurodegenerative Delay (Mind) Diet and Metabolic Health Status in Adolescents With Overweight and Obesity: Results From a Cross-Sectional Study in Iran, British Journal of Nutrition (2024)
10. Associations of Fruit and Vegetable Intake With Metabolic Health Status in Overweight and Obese Youth, Annals of Nutrition and Metabolism (2023)
11. Dietary Total, Plant and Animal Protein Intake in Relation to Metabolic Health Status in Overweight and Obese Adolescents, Scientific Reports (2022)
12. Dairy Intake in Relation to Metabolic Health Status in Overweight and Obese Adolescents, Scientific Reports (2022)
13. Association Between Dietary Acid Load and Metabolic Health Status in Overweight and Obese Adolescents, Scientific Reports (2022)
14. Association Between Plant-Based Diets and Metabolic Health Status in Adolescents With Overweight and Obesity, Scientific Reports (2022)
15. Association Between Methyl Donor Nutrients And Metabolic Health Status in Overweight and Obese Adolescents, Scientific Reports (2022)
16. The Relation Between Dietary Phytochemical Index and Metabolic Health Status in Overweight and Obese Adolescents, Scientific Reports (2023)
17. Association Between Alternative Healthy Eating Index (Ahei) With Metabolic Health Status in Adolescents With Overweight and Obesity, BMC Public Health (2024)
18. Risk Factors, Cutoff Points, and Definition of Metabolically Healthy/Unhealthy Obesity in Children and Adolescents: A Scoping Review of the Literature, Obesity Reviews (2023)
19. Association Between Mediterranean Diet and Metabolic Health Status Among Adults Was Not Mediated Through Serum Adropin Levels, BMC Public Health (2025)
20. Association of Dietary Behaviors, Biochemical, and Lifestyle Factors With Metabolic Phenotypes of Obesity in Children and Adolescents, Diabetology and Metabolic Syndrome (2020)
21. Metabolic Syndrome and Cardiovascular Risk Factors in a National Sample of Adolescent Population in the Middle East and North Africa: The Caspian Iii Study, International Journal of Endocrinology (2013)
22. Dietary Predictors of Overweight and Obesity in Iranian Adolescents, Iranian Red Crescent Medical Journal (2016)
23. Dietary Total Antioxidant Capacity in Relation to Metabolic Health Status in Overweight and Obese Adolescents, Nutrition journal (2022)
24. Tri-Ponderal Mass Index and Body Mass Index in Prediction of Pediatric Metabolic Syndrome: The Caspian-V Study, Archives of Endocrinology and Metabolism (2020)
25. Height-Adjusted Percentiles Evaluated Central Obesity in Children and Adolescents More Effectively Than Just Waist Circumference, Acta Paediatrica, International Journal of Paediatrics (2017)
26. Association of Anthropometric Indices With Metabolic Phenotypes of Obesity in Children and Adolescents: The Caspian-V Study, Frontiers in Endocrinology (2019)
27. The Effect of Mediterranean Diet on Inflammatory Biomarkers and Components of Metabolic Syndrome in Adolescent Girls, Journal of Endocrinological Investigation (2023)
28. The Relationship Between Dietary Patterns and Metabolic Phenotypes: A Cross-Sectional Study in a Representative Sample of Iranian Industrial Employees, Metabolic Syndrome and Related Disorders (2024)
29. Adherence to Mediterranean Dietary Pattern Is Inversely Associated With Depression, Anxiety and Psychological Distress, Nutritional Neuroscience (2021)
30. Association of Serum 25-Hydroxyvitamin D Level With Metabolic Phenotypes of Obesity in Children and Adolescents: The Caspian-V Study, Frontiers in Endocrinology (2020)
31. First Nationwide Study of the Prevalence of the Metabolic Syndrome and Optimal Cutoff Points of Waist Circumference in the Middle East: The National Survey of Risk Factors for Noncommunicable Diseases of Iran, Diabetes Care (2009)
32. Underweight, Overweight and Obesity Among Zaboli Adolescents: A Comparison Between International and Iranians' National Criteria, International Journal of Preventive Medicine (2013)
33. Association Between Junk Food Consumption and Cardiometabolic Risk Factors in a National Sample of Iranian Children and Adolescents Population: The Caspian-V Study, Eating and Weight Disorders (2020)
34. Joint Association of Screen Time and Physical Activity With Cardiometabolic Risk Factors in a National Sample of Iranian Adolescents: The Caspianiii Study, PLoS ONE (2016)
35. Association of Nutrient Patterns With Anthropometric Indices in Children and Adolescents: The Weight Disorders Survey of the Caspian-Iv Study, Mediterranean Journal of Nutrition and Metabolism (2019)
36. Obesity and Associated Modifiable Environmental Factors in Iranian Adolescents: Isfahan Healthy Heart Program - Heart Health Promotion From Childhood, Pediatrics International (2003)
37. Adherence to Lifelines Diet Score and Risk Factors of Metabolic Syndrome Among Overweight and Obese Adults: A Cross-Sectional Study, Frontiers in Nutrition (2022)
38. Obesity and Metabolic Syndrome Among a Representative Sample of Iranian Adolescents, Southeast Asian Journal of Tropical Medicine and Public Health (2012)
39. Prevalence of Different Metabolic Phenotypes of Obesity in Iranian Children and Adolescents: The Caspian V Study, Journal of Diabetes and Metabolic Disorders (2018)
40. Association of Anthropometric Indices With Continuous Metabolic Syndrome in Children and Adolescents: The Caspian-V Study, Eating and Weight Disorders (2018)
41. The Association of Dietary Carbohydrate Quality and Quantity With Obesity Among Iranian Adolescents: A Case-Control Study, BMC Pediatrics (2024)
42. Association of Short Stature and Obesity With Cardio-Metabolic Risk Factors in Iranian Children and Adolescents: The Caspian-V Study, Journal of Diabetes and Metabolic Disorders (2021)
43. Association of Anthropometric Measures With Cardiovascular Risk Factors and Metabolic Syndrome in Normal-Weight Children and Adolescents: The Caspian Iii Study, Obesity Facts (2013)
44. Childhood Overweight and Obesity and Associated Factors in Iranian Children and Adolescents: A Multilevel Analysis; the Caspian-Iv Study, Frontiers in Pediatrics (2018)
45. Metabolic Syndrome and Associated Factors in Iranian Children and Adolescents: The Caspian-V Study, Journal of Cardiovascular and Thoracic Research (2018)
46. Dietary Glycemic Index and Insulin Index in Association With Incident Type 2 Diabetes Mellitus in Adults, British Journal of Nutrition (2025)
47. The Prevalence of Impaired Fasting Glucose and Type 2 Diabetes in a Population-Based Sample of Overweight/Obese Children in the Middle East, Pediatric Diabetes (2010)
48. Trend in the Prevalence of Obesity and Overweight Among Iranian Children and Adolescents: A Systematic Review and Meta-Analysis, Nutrition (2014)
49. First Nationwide Survey of Prevalence of Weight Disorders in Iranian Children at School Entry, World Journal of Pediatrics (2010)
50. The Prevalence of Childhood Underweight, Overweight, and Obesity Based on Four Different Criteria, Journal of Nutrition and Food Security (2020)