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Preparation and Pharmaceutical Evaluation of Nicotinamide Stick for Eradication of Staphylococcus Epidermidis



Shahtalebi MA1 ; Bahrinajafi R2 ; Nahavandi S2
Authors
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Authors Affiliations
  1. 1. Departments of Pharmaceutics, Isfahan University of Medical Sciences, Isfahan, Iran
  2. 2. School of Pharmacy and Pharmaceutical Sciences, Isfahan University of Medical Sciences, Isfahan, Iran

Source: Journal of Research in Medical Sciences Published:2014

Abstract

Background: Staphylococcus epidermidis is a part of the skin’s normal flora that can cause acne. This study was designed to evaluate the efficacy of nicotinamide as a stick in eradication of staphylococcus. Materials and Methods: For evaluating of Anti-microbial effect on S. epidermidis used well plate method. We chose five plates for nicotinamide and five for mupirocin. The zones of inhibition were measured and compared. Results: The results showed nicotinamide stick had anti-microbial effects, but in comparison to mupirocin it was significantly less (P = 0.003). Conclusion: Nicotinamide stick was made and evaluated. This study showed that nicotinamide had anti-microbial effect on staphylococcus. © 2014 Isfahan University of Medical Sciences(IUMS). All rights reserved.
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