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Correlation Between Vitamin D Level and Coronary Artery Calcification Publisher



Sajjadieh H1 ; Sajjadieh A1 ; Koopaei Z2 ; Oveisgharan S3
Authors
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Authors Affiliations
  1. 1. Department of Internal Medicine, Isfahan University of Medical Science, Isfahan, Iran
  2. 2. Department of Pathology, Isfahan University of Medical Science, Isfahan, Iran
  3. 3. Rush Alzheimer s Disease Center, Rush University Medical Center, Chicago, IL, United States

Source: Journal of Research in Medical Sciences Published:2020


Abstract

Considering the role of Vitamin D in cardiovascular disease (CVD) and the relationship between coronary artery calcification (CAC) and CVD, we aimed to investigate the association between the serum level of Vitamin D and CAC. Materials and Methods: This was a cross-sectional study on 67 consecutive patients who were referred for performing computed tomography angiography. We used Spearman correlation to evaluate the relationship between Vitamin D and CAC and then linear regressions to control for demographics and vascular risk factors. Results: There was no association between CAC and Vitamin D levels (Spearman coefficient = -0.03, P = 0.805). After controlling for age, sex, hypertension, hyperlipidemia, diabetes mellitus, and smoking, there was still no association between Vitamin D and CAC score (estimate = 0.001, S. E. = 0.020, P = 0.942). Conclusion: We did not find the association between the serum level of Vitamin D and coronary artery calcification. © 2020 BMJ Publishing Group. All rights reserved.
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