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Plant-Derived Edible Nanoparticles and Mirnas: Emerging Frontier for Therapeutics and Targeted Drug-Delivery Publisher



Iravani S1 ; Varma RS2
Authors
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Authors Affiliations
  1. 1. Faculty of Pharmacy and Pharmaceutical Sciences, Isfahan University of Medical Sciences, Hezar Jarib Street, Isfahan, 81746-73461, Iran
  2. 2. Regional Centre of Advanced Technologies and Materials, Department of Physical Chemistry, Faculty of Science, Palacky University in Olomouc, SlechtiteluIs 27, Olomouc, 783 71, Czech Republic

Source: ACS Sustainable Chemistry and Engineering Published:2019


Abstract

Rigorous and timely studies have been conducted to develop natural and green nanomedicines wherein plant-derived edible nanoparticles (PDENs) have a great potential to be applied for targeted therapeutic delivery systems, because of their exclusive characteristics, namely desirable nanoparticle morphologies, environmentally safe and nonhazardous nature, appropriate tissue-specific targeting, and eminent potential for industrial pharmaceutical production. These nanoparticles can be exploited for drug transportation with distinctive benefits for treatment of diseases like cancers. In this Perspective, the properties and applications of PDENs are discussed with latest developments including the recent trends in plant-derived edible exosome-like nanoparticles and miRNAs. © 2019 American Chemical Society.
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