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Measuring the Burden of Comorbidity for Ischaemic Heart Disease and Four Common Non-Communicable Diseases in Iran, 1990-2017: A Modelling Study Based on Global Burden of Diseases Data Publisher Pubmed



Mansourian M1 ; Ghasemi K2 ; Haghdoost A3 ; Kopec JA4 ; Sarrafzadegan N4, 5 ; Islam SMS6
Authors
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Authors Affiliations
  1. 1. Barcelona Tech (UPC), Universitat Politecnica de Catalunya, Barcelona, Spain
  2. 2. Cardiovascular Research Institute, Interventional Cardiology Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
  3. 3. Modeling in Health Research Center, Institute for Futures Studies in Health, Kerman University of Medical Sciences, Kerman, Iran
  4. 4. School of Population and Public Health, The University of British Columbia, Vancouver, BC, Canada
  5. 5. Cardiovascular Research Institute, Isfahan Cardiovascular Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
  6. 6. Institute for Physical Activity and Nutrition, Deakin University, Burwood, VIC, Australia

Source: BMJ Open Published:2022


Abstract

Objective This modelling study aimed to estimate the comorbidity burden for four common non-communicable diseases with ischaemic heart diseases (IHD) in Iran during a period of 28 years. Design Analysis of the burden of comorbidity with IHD based on data included prevalence rates and the disability weight (DW) average for calculating years lived with disability (YLDs) from the Iran population based on the Global Burden of Disease (GBD) study. Setting Population-based available data in GBD 2017 study of Iran population. Participant The source of data was the GBD 2017 Study. We evaluated IHD, major depressive disorder (MDD), diabetes mellitus (DM), ischaemic stroke (IS), and osteoarthritis (OA) age-standardised prevalence rates and their DW. Main outcome measures A new formula that modified the GBD calculator was used to measure the comorbidity YLDs. In the new formula, some multipliers were considered, measuring the departure from independence. Result The contribution of total comorbidity for each combination of IHD with DM, MDD, IS and OA was 2.5%, 2.0%, 1.6% and 2.9%, respectively. The highest YLD rates were observed for IHD_MDD, 16.5 in 1990 and 17.0 in 2017. This was followed by IHD_DM, from 11.5 to 16.9 per 100 000. The YLD rates for IHD_OA changed slightly (6.5-6.7) per 100 000, whereas there was a gradual reduction in the trends of IHD-IS, from 4.0-4.5 per 100 000. Conclusion Of the four comorbidities studied, the highest burden was due to the coexistence of MDD with IHD. Our results highlight the importance of addressing the burden of comorbidities when studying the burden of IHD or any other non-communicable disease. ©
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