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Diet in Relation to Metabolic, Sleep and Psychological Health Status (Dimets): Protocol for a Cross-Sectional Study Publisher Pubmed



Poursalehi D1 ; Shahdadian F2 ; Hajhashemy Z1 ; Lotfi K3 ; Moradmand Z4 ; Rouhani P4 ; Mohammadi S4 ; Mokhtari E4 ; Saneei P1
Authors
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Authors Affiliations
  1. 1. Isfahan University of Medical Sciences, Isfahan, Iran
  2. 2. Department of Clinical Nutrition Isfahan University of Medical Sciences, Isfahan, Iran
  3. 3. Department of Community Nutrition, Tehran University of Medical Sciences, Tehran, Iran
  4. 4. Department of Community Nutrition, Isfahan University of Medical Sciences, Isfahan, Iran

Source: BMJ Open Published:2023


Abstract

Introduction Metabolic disturbances are of major health concerns in the world. In addition to their high prevalence, these disorders have substantial roles in developing other physical and mental diseases. Diet could have a considerable influence on managing the progression of these conditions and their consequent health-related effects. The aim of the ‘Diet in relation to Metabolic, sleep and psychological health Status’ Project is to explore the association of nutrition with metabolic, sleep and mental health, considering potential mediators including brain-derived neurotrophic factor (BDNF) and adropin. Methods and analysis This cross-sectional study will be conducted on adults (20–65 years) working in schools of Isfahan, Iran. A multistage cluster random sampling method will be used to select participants. Anthropometric, body composition and biochemical values including fasting blood glucose, lipid profile, 25-hydroxy vitamin D, insulin, BDNF, adropin, malondialdehyde, superoxide dismutase, glutathione peroxidase, uric acid, creatinine and C reactive protein will be measured for each participant. National Cholesterol Education Program and Adult Treatment Panel III will be considered to define metabolic syndrome. Diet will be assessed through a validated Food Frequency Questionnaire. Furthermore, sleep status, mental health, quality of life, physical activity and demographic status of individuals will be assessed by validated questionnaires. The collected data will be analysed using appropriate statistical methods. Ethics and dissemination The study protocol was approved by the local Ethics Committee of Isfahan University of Medical Sciences. All participants will provide written informed consent. Dissemination will be through conference presentations and publications in peer-reviewed journals. © Author(s)
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