Isfahan University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
Evaluation of Lipid Profile Changes in Patients During One Year After the Onset of Peritoneal Dialysis Publisher



Seirafian S1 ; Tabatabaei P2
Authors
Show Affiliations
Authors Affiliations
  1. 1. Department of Nephrology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
  2. 2. Student Research Committee, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

Source: Journal of Isfahan Medical School Published:2020


Abstract

Background: Chronic renal failure refers to an irreversible deterioration of renal function that follows a progressive course and ultimately leads to necessity of dialysis in most of patients. As some studies have indicated that the mentioned patients may eventually develop lipid profile abnormalities, the present study aimed to evaluate the effective factors in lipid profile changes in these patients over one year. Methods: In this cross-sectional study, 251 patients under peritoneal dialysis, whose profiles were available in the archives of Alzahra hospital, Isfahan, Iran, during 2018-2019, were randomly selected. Demographic data and lipid profile of these patients including total cholesterol (TCH), low-density lipoprotein (LDL), high-density lipoprotein (HDL), triglyceride (TG), and blood glucose levels were recorded and analyzed at baseline as well as six months and one year after the start of dialysis. Findings: Changes in the lipid profile of the patients during one year of dialysis were significant (P < 0.050). Sexuality had a direct and significant relationship with all the changes in lipid profile items (P < 0.001). In addition, as well as an increase in the hemoglobin (Hb) level, it had a direct and significant relationship with elevated levels of LDL, TCH, and TG (P < 0.001 for all). Moreover, blood glucose level had a significant relationship with increased levels of TCH (P = 0.040) and TG (P = 0.014). Finally, dialysis solution with 2.5% and 4.25% dextrose had a significant and direct effect on increasing the levels of TCH (P =0.035) and LDL (P = 040), respectively. Conclusion: According to the results of the present study, the lipid profiles of patients undergoing peritoneal dialysis revealed significant changes. The most significant factors associated with lipid profiles were the type of dialysis solution, and the levels of blood glucose and Hb. © 2016 Isfahan University of Medical Sciences(IUMS). All rights reserved.
Related Docs
View other Related Docs
1. The Prevalence of Metabolic Syndrome in Patients on Hemodialysis and Peritoneal Dialysis: A Comparative Study, Journal of Isfahan Medical School (2012)
2. Carotid Intima-Media Thickness in Children With End-Stage Renal Disease on Dialysis, Indian Journal of Nephrology (2010)
3. Correlation of Serum Magnesium and Blood Lipid Profile in Under- Peritoneal Dialysis and Hemodialysis Patients, Journal of Isfahan Medical School (2014)
4. Chronic Kidney Disease in Iran: First Report of the National Registry in Children and Adolescences, Urology Journal (2021)
5. Association Between Neutrophil Geletinase-Associated Lipocalin and Iron Deficiency Anemia in Children on Chronic Dialysis, Journal of Research in Medical Sciences (2014)
6. Association of Dietary Acid Load With Cardiovascular Disease Risk Factors in Patients With Diabetic Nephropathy, Nutrition (2015)
7. Lipid Variability and Risk of Microvascular Complications in Patients With Diabetes: A Systematic Review and Meta-Analysis, BMC Endocrine Disorders (2024)
8. Effects of Garlic Supplement on Dialysis Efficiency, Serum Albumin, Parathyroid Hormone, Calcium, Phosphorus and C-Reactive Protein and Blood Lipid Profile in Chronic Hemodialysis Patients: A Double-Blind Randomized Clinical Trial, Iranian Journal of Nutrition Sciences and Food Technology (2024)
Experts (# of related papers)
View all Related Experts
Mojgan Mortazavi (24)
Mohammad Hossein Rouhani (13)
Other Related Docs
9. Evaluation of Factors Related to Depression in Peritoneal Dialysis Patients: A Multicenter Cross-Sectional Study, Renal Replacement Therapy (2023)
10. Changes in Lipid Profile of Patients Referred to a Cardiac Rehabilitation Program, European Journal of Preventive Cardiology (2008)
11. The Association Between Lipid Profile, Oxidized Ldl and the Components of Metabolic Syndrome With Serum Mineral Status and Kidney Function in Individuals With Obesity, BMC Research Notes (2023)
12. Renal Function After Renal Transplantation in Patients With Metabolic Syndrome, Journal of Isfahan Medical School (2018)
13. Effect of the Omega-3 Fatty Acid Plus Vitamin E Supplementation on Subjective Global Assessment Score, Glucose Metabolism, and Lipid Concentrations in Chronic Hemodialysis Patients, Molecular Nutrition and Food Research (2016)
14. Clinical Trial of the Effects of Coenzyme Q10 Supplementation on Glycemic Control and Markers of Lipid Profiles in Diabetic Hemodialysis Patients, International Urology and Nephrology (2018)
15. Association Between Nutritional, Inflammatory and Oxidative Status (Nios) and Risk of Adverse Outcomes in Patients on Haemodialysis (Hd): The Nios-Hd Prospective Cohort Study Protocol, BMJ Open (2022)
16. Comparison of Vascular Access Use in Hemodialysis Patients in Isfahan in 2003 and 2013, Indian Journal of Nephrology (2015)
17. The Comparative Evaluation of Patients' Body Dry Weight Under Hemodialysis Using Two Methods: Bioelectrical Impedance Analysis and Conventional Method, Journal of Research in Medical Sciences (2012)
18. Dietary Acid Load and Markers of Malnutrition, Inflammation, and Oxidative Stress in Hemodialysis Patients, Frontiers in Nutrition (2024)
19. Low Levels of High-Density Lipoprotein Cholesterol Do Not Predict the Incidence of Type 2 Diabetes in an Iranian High-Risk Population: The Isfahan Diabetes Prevention Study, Review of Diabetic Studies (2016)
20. Association of Dietary Acid Load With Cardiovascular Risk Factors and the Prevalence of Metabolic Syndrome in Iranian Women: A Cross-Sectional Study, Nutrition (2019)
21. Serum Zinc Levels in Hemodialysis and Peritoneal Dialysis Patients: A Retrospective Observational Study, Journal of Research in Medical Sciences (2024)
22. Effects of Oral L-Carnitine Supplementation on Lipid Profile, Anemia, and Quality of Life in Chronic Renal Disease Patients Under Hemodialysis: A Randomized, Double-Blinded, Placebo-Controlled Trial, Journal of Nutrition and Metabolism (2012)
23. Control of Dyslipidemia Among Type 2 Diabetic Patients in Isfahan, 5 Years Follow-Up (1999-2003), Iranian Journal of Diabetes and Lipid Disorders (2007)
24. Dietary Patterns in Relation to Lipid Profiles Among Iranian Adults, Journal of Cardiovascular and Thoracic Research (2019)
25. Effect of Vitamin C Supplementation on Oxidative Stress and Lipid Profiles in Hemodialysis Patients, International Journal for Vitamin and Nutrition Research (2009)
26. Association Between the Index of Nutritional Quality and Lipid Profile in Adult Women, Endocrinology, Diabetes and Metabolism (2022)
27. Thyroid Function Markers in Patients Receiving Hemodialysis and Peritoneal Dialysis for Chronic Kidney Disease, Journal of Isfahan Medical School (2013)
28. The Association Between Plant and Animal Protein Intake and Quality of Life in Patients Undergoing Hemodialysis, Frontiers in Nutrition (2023)
29. Dietary Calcium Intake in Relation to Blood Lipids and Lipoproteins Profiles: A Systematic Review and Meta-Analysis of Epidemiologic Studies, Nutrition, Metabolism and Cardiovascular Diseases (2022)
30. Direct Association Between High Fat Dietary Pattern and Risk of Being in the Higher Stages of Chronic Kidney Disease, International Journal for Vitamin and Nutrition Research (2019)
31. Association of Cardiac Troponin I Level With In-Hospital and Late Mortality in Dialysis Patients, Journal of Research in Medical Sciences (2025)
32. Association Between Adherence to the Mediterranean Diet and Renal Function Biomarkers and Cardiovascular Risk Factors Among Diabetic Patients With Nephropathy, Clinical Nutrition ESPEN (2020)
33. Effects of Carnitine Supplement on Dyslipidemia and Anemia in Hemodialysis Patients, Journal of Isfahan Medical School (2011)
34. Dietary Nutrients’ Intake and Sleep Quality in Peritoneal Dialysis Patients, Sleep Science (2021)
35. The Ratio of Dietary Diversity Score Versus Energy Density in Relation to Anthropometric and Biochemical Variables Among Patients With Chronic Kidney Diseases, Progress in Nutrition (2019)
36. Is Family History of Premature Cardiovascular Diseases Appropriate for Detection of Dyslipidemic Children in Population-Based Preventive Medicine Programs? Caspian Study, Pediatric Cardiology (2006)
37. The Relationship Between Serum Ghrelin Levels and Bone Metabolism Markers and Severity Anemia in Non-Diabetic Hemodialysis Patients; a Pilot Study, Journal of Nephropathology (2018)
38. Mortality and Disability-Adjusted Life Years in North Africa and Middle East Attributed to Kidney Dysfunction: A Systematic Analysis for the Global Burden of Disease Study 2019, Clinical Kidney Journal (2024)
39. Dietary Acid Load Modifies the Effects of Apoa2–265 T > C Polymorphism on Lipid Profile and Serum Leptin and Ghrelin Levels Among Type 2 Diabetic Patients, BMC Endocrine Disorders (2022)
40. Serum Leptin Level Has a Positive Correlation With Bmi and Creatinine Clearance in Capd Patients, Bratislava Medical Journal (2012)
41. An Updated Systematic Review on the Effects of Aerobic Exercise on Human Blood Lipid Profile, Current Problems in Cardiology (2023)
42. Utility of Serum Lipid Ratios for Predicting Incident Type 2 Diabetes: The Isfahan Diabetes Prevention Study, Diabetes/Metabolism Research and Reviews (2016)
43. A Comparison of the Quality of Life of the Patients Undergoing Hemodialysis Versus Peritoneal Dialysis and Its Correlation to the Quality of Dialysis, Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia (2016)
44. Dietary Acid Load, Kidney Function and Risk of Chronic Kidney Disease: A Systematic Review and Meta-Analysis of Observational Studies, International Journal for Vitamin and Nutrition Research (2021)
45. Association of Lipid Profile With Type 2 Diabetes in First-Degree Relatives: A 14-Year Follow-Up Study in Iran, Diabetes, Metabolic Syndrome and Obesity (2020)
46. Comparison of Three Diet Quality Indices for Patients With Chronic Kidney Disease, Archives of Iranian Medicine (2017)
47. Association of Lipid Accumulation Product With Cardio-Metabolic Risk Factors in Postmenopausal Women, Acta Medica Iranica (2016)
48. Nutritional Vitamin D Supplementation in Chronic Hemodialysis: An Uncontrolled Open-Label Trial, Journal of Education and Health Promotion (2023)
49. Assessment of Hemodialysis Adequacy and Its Relationship With Individual and Personal Factors, Iranian Journal of Nursing and Midwifery Research (2016)
50. Mean Serum Lipid Levels in Iranian Adult Populations: A Systematic Review and Meta-Analysis, Clinical Lipidology (2015)