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The Relationship of Laboratory Results and Cognitive Function in Patient With Type I and Type Ii Diabetes Mellitus



Roohollahikoshteli A1 ; Najafi M2 ; Kachooei A3, 5 ; Mollabashi Z4 ; Iraj B3, 5
Authors
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Authors Affiliations
  1. 1. School of Medicine and Students Research Committee, Isfahan University of Medical Sciences, Isfahan, Iran
  2. 2. Department of Psychiatry, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
  3. 3. Department of Endocrinology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
  4. 4. Department of Microbiology, Isfahan University of Medical Sciences, Isfahan, Iran
  5. 5. Department of Endocrinology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

Source: Journal of Isfahan Medical School Published:2013

Abstract

This study established to investigate the association among exact blood glucose control, performative and cognitive values, and patients' demographic properties in patient with type I and type II diabetes mellitus. Methods: This episodic descriptive-analytic study was performed on 73 patients with type I and type II diabetes mellitus in Metabolism and Endocrinology Research Center of Isfahan University of Medical Sciences, Iran. The patients were assessed using continuous performance test (CPT); the association of the results and recent laboratory values, such as hemoglobin A1c (HbA1c), 2-hour postprandial blood sugar (2-h PPBS), fasting blood sugar (FBS), in the recent 6 months and also, patients' demographic properties and diabetes type was evaluated by Student-t, ANOVA and Pearson's coefficient correlation tests. Findings: The impulsivity value in type I diabetes was lower than type II (P = 0.034); there was a direct and meaningful association between impulsivity value and taking neutral protamine Hagedorn (NPH) insulin. There was a direct and meaningful association among impulsivity value, recent FBS, 2-h PPBS, HbA1C levels and patients' age, also, among mean values of reaction rate and patients' age and the age of diagnosing the disease (P < 0.05 for all). Conclusion: The findings indicate that cognitive impairment in type II diabetes and elderly are more than other ages which is in favor of association between exact blood glucose control, and insulin NPH taking with decreasing in cognitive impairments.
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