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Synthesis and in Vitro Evaluation of Electrodeposited Barium Titanate Coating on Ti6al4v Publisher



Rahmati S1 ; Basiriani MB2 ; Rafienia M3 ; Yaghini J4 ; Raeisi K2
Authors
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Authors Affiliations
  1. 1. Department of Biomaterials, Nanotechnology and Tissue Engineering, School of Advanced Medical Technologies, Isfahan University of Medical Sciences, Isfahan, 81744176, Iran
  2. 2. Department of Materials Engineering, Isfahan University of Technology, Isfahan, 8415683111, Iran
  3. 3. Biosensor Research Center, Isfahan University of Medical Sciences, P. O. Box 64716, Isfahan, 81744176, Iran
  4. 4. Department of Periodontology, School of Dentistry, Dental Implant Research Center, Isfahan University of Medical Sciences, Isfahan, 81744176, Iran

Source: Journal of Medical Signals and Sensors Published:2016


Abstract

Osseointegration has been the concern of implantology for many years. Researchers have used various ceramic coatings for this purpose; however, piezoelectric ceramics (e.g., barium titanate [BTO]) are a novel field of interest. In this regard, BTO (BaTiO 3 ) coating was fabricated by electrophoretic deposition on Ti6Al4V medical alloy, using sol-gel-synthesized nanometer BTO powder. Structure and morphologies were studied using X-ray diffraction and scanning electron microscopy (SEM), respectively. Bioactivity response of coated samples was evaluated by SEM and inductively coupled plasma (ICP) analysis after immersion in simulated body fluid (SBF). Cell compatibility was also studied via MTT assay and SEM imaging. Results showed homogenous coating with cubic structure and crystallite size of about 41 nm. SEM images indicated apatite formation on the coating after 7 days of SBF immersion, and ICP analysis approved ions concentration decrement in SBF. Cells showed flattened morphology in intimate contact with coating after 7 days of culture. Altogether, coated samples demonstrated appropriate bioactivity and biocompatibility. © 2016 Journal of Medical Signals & Sensors.
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