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Characterization and in Vitro Evaluation of Nanostructure Barium Titanate Coating on Ti6al4v



Rahmati S1 ; Basiriani MB2 ; Rafienia M3 ; Yaghini J4 ; Raeissi K2 ; Hosseini S5 ; Kabiri S6
Authors
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Authors Affiliations
  1. 1. Department of Biomaterials, Nanotechnology and Tissue Engineering, School of Advanced Medical Technologies, Isfahan University of Medical Sciences, Isfahan, 81744176, Iran
  2. 2. Department of Materials Engineering, Isfahan University of Technology, Isfahan, 84156-83111, Iran
  3. 3. Biosensor Research Center, Isfahan University of Medical Sciences, Isfahan, 81744176, Iran
  4. 4. Dental Implant Research Center and Department of Periodontology, School of Dentistry, Isfahan University of Medical Sciences, Isfahan, 81744176, Iran
  5. 5. School of Dentistry, Isfahan University of Medical Sciences, Isfahan, Iran
  6. 6. Orthodontic Department, Dental school, Shahid Beheshti University of Medical Sciences, Tehran, 81744176, Iran

Source: Journal of Ceramic Processing Research Published:2016

Abstract

Osseointegration has been the concern of implantology for many years. Researchers have used various ceramic coatings for this purpose however piezoelectric ceramics (e.g. Barium titanate) are a novel field of interest. In this regard, Barium titanate (BaTiO3, BTO) coating were fabricated by electrophoretic deposition (EPD) on Ti6Al4V medical alloy, using sol-gel synthesized nanometer BTO powder. Structure and morphologies were studied using X-ray diffraction (XRD) and scanning electron microscopy (SEM) respectively. Results showed homogenous coating with cubic structure and crystallite size of about 41 nm. Bioactivity response of coated samples while immersion in simulated body fluid (SBF) were evaluated by SEM and inductively coupled plasma (ICP) analysis. Cell compatibility was also studied via MTT assay and SEM imaging. SEM images indicated Apatite formation on the coating after 7 days of SBF immersion, and ICP analysis approved ions concentration decrement in SBF. Cells showed flattened morphology in intimate contact with coating after 12 h of culture. Altogether, coated samples demonstrated appropriate bioactivity and biocompatibility. © 2016, Hanyang University. All rights reserved.
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