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The Association Between Serum Lactate Level and Post Cabg Complications in Cardiac Patients



Mirmohammadsadeghi M1 ; Etesampour A2 ; Gharipour M3 ; Saeidi M1 ; Mirmohammadsadeghi P4 ; Kiani A5 ; Shamsolkotabi H2 ; Farahmand N2 ; Tabib AA3
Authors
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Authors Affiliations
  1. 1. Department of Cardiosurgery, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
  2. 2. Delasa Research Center, Isfahan, Iran
  3. 3. Isfahan Cardiovascular Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
  4. 4. School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
  5. 5. Isfahan University of Medical Sciences, Isfahan, Iran

Source: Journal of Isfahan Medical School Published:2011

Abstract

Background: The aim of this study was to evaluate the relationship between postoperative serum lac-tate levels and outcome in patients undergoing coronary artery bypass graft surgery (CABG) and verify the clinical impact of hyperlactatemia (HL) during CABG in terms of postoperative morbidity and mortality rate. Methods: In this prospective study, 92 patients underwent open heart surgery. Demographic data, lac-tate levels, pH, 48 hours serum creatinin after surgery (mg per cent), left ventricular ejection fraction, Inotropic Drugs and the duration of use and the duration of intensive care unit (ICU) admission t and deaths were collected. Finding: Mortality rate was 3.3 percent, the average duration of hospitalization was 8.8 days and the duration of ICU admission was 47.27 hours. In 82.6% of the patients increased lactic acid was observed; while 17.4% of patients had a low lactate serum concentration during ICU admission. Conclusion: The findings of this study showed an association between lactate serum levels and the duration of ICU admission and duration of hospitalization, so hyperlactatemia could be a prognostic factor and could predict the mortality and the severity of complications in the patients undergone CABG.
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