Isfahan University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
Association of Lipid Accumulation Product With Cardio-Metabolic Risk Factors in Postmenopausal Women Pubmed



Shabestari AN1 ; Asadi M2, 3 ; Jouyandeh Z4 ; Qorbani M5, 6 ; Kelishadi R7
Authors
Show Affiliations
Authors Affiliations
  1. 1. Department of Gerontology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Osteoporosis Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran
  3. 3. Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran
  4. 4. Obesity and Eating Habit Research Center, Endocrinology and Metabolism Institute, Tehran University of Medical Sciences, Tehran, Iran
  5. 5. Department of Medicine, School of Medicine, Karaj University of Medical Sciences, Alborz, Iran
  6. 6. Department of Epidemiology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran
  7. 7. Department of Pediatrics, Child Growth and Development Research Center, Isfahan University of Medical Sciences, Isfahan, Iran

Source: Acta Medica Iranica Published:2016


Abstract

The lipid accumulation product is a novel, safe and inexpensive index of central lipid over accumulation based on waist circumference and fasting concentration of circulating triglycerides. This study was designed to investigate the ability of lipid accumulation product to predict Cardio-metabolic risk factors in postmenopausal women. In this Cross-sectional study, 264 postmenopausal women by using convenience sampling method were selected from menopause clinic in Tehran. Cardio-metabolic risk factors were measured, and lipid accumulation product (waist-58×triglycerides [nmol/L]) was calculated. Optimal cut-off point of lipid accumulation product for predicting metabolic syndrome was estimated by ROC (Receiveroperating characteristic) curve analysis. Metabolic syndrome was diagnosed in 41.2% of subjects. Optimal cut-off point of lipid accumulation product for predicting metabolic syndrome was 47.63 (sensitivity:75%; specificity:77.9%). High lipid accumulation product increases risk of all Cardio-metabolic risk factors except overweight, high Total Cholesterol, high Low Density Lipoprotein Cholesterol and high Fasting Blood Sugar in postmenopausal women. Our findings show that lipid accumulation product is associated with metabolic syndrome and some Cardio-metabolic risk factors Also lipid accumulation product may have been a useful tool for predicting cardiovascular disease and metabolic syndrome risk in postmenopausal women. © 2016 Tehran University of Medical Sciences. All rights reserved.
Related Docs
View other Related Docs
1. The Association Between Hypertriglyceridemic Waist Phenotype, Menopause, and Cardiovascular Risk Factors, Archives of Iranian Medicine (2013)
2. Hypertriglyceridemic Waist Phenotype, Markers of Systemic Inflammation and Endothelial Dysfunction Among Women, Iranian Journal of Diabetes and Lipid Disorders (2007)
3. Increased Levels of Inflammation Among Women With Enlarged Waist and Elevated Triglyceride Concentrations, Annals of Nutrition and Metabolism (2010)
4. Predictors of Metabolic Syndrome in the Iranian Population: Waist Circumference, Body Mass Index, or Waist to Hip Ratio?, Cholesterol (2013)
5. Lipid Accumulation Product and Visceral Adiposity Index for Incidence of Cardiovascular Diseases and Mortality; Results From 13 Years Follow-Up in Isfahan Cohort Study, Obesity Science and Practice (2024)
6. The First Cut-Off Points for Generalized and Abdominal Obesity in Predicting Lipid Disorders in a Nationally Representative Population in the Middle East: The National Survey of Risk Factors for Non-Communicable Diseases of Iran, Archives of Medical Science (2009)
7. Determinants of Incident Metabolic Syndrome in a Middle Eastern Population: Isfahan Cohort Study, Metabolic Syndrome and Related Disorders (2017)
8. Mean Serum Lipid Levels in Iranian Adult Populations: A Systematic Review and Meta-Analysis, Clinical Lipidology (2015)
Experts (# of related papers)
View all Related Experts
Nizal Sarrafzadegan (94)
Roya Kelishadi (70)
Other Related Docs
9. Association of Quality and Quantity of Macronutrients Intake With Obesity, New Anthropometric Indices, Lipid Accumulation, and Blood Lipid Risk Index in Tehranian Women, Food Science and Nutrition (2024)
10. Association Between the Index of Nutritional Quality and Lipid Profile in Adult Women, Endocrinology, Diabetes and Metabolism (2022)
11. Predicting the 10-Year Incidence of Dyslipidemia Based on Novel Anthropometric Indices, Using Data Mining, Lipids in Health and Disease (2024)
12. Association Between Serum Cytokine Concentrations and the Presence of Hypertriglyceridemia, Clinical Biochemistry (2016)
13. Accuracy of Novel Anthropometric Indices for Assessing the Risk for Progression of Prediabetes to Diabetes; 13 Years of Results From Isfahan Cohort Study, Archives of Endocrinology and Metabolism (2024)
14. Consumption of Energy-Dense Diets in Relation to Metabolic Syndrome and Inflammatory Markers in Iranian Female Nurses, Public Health Nutrition (2017)
15. The Effect of a Moderately Restricted Carbohydrate Diet on Cardiometabolic Risk Factors in Overweight and Obese Women With Metabolic Syndrome: A Randomized Controlled Trial, Clinical Therapeutics (2023)
16. The Impact of Pycnogenol Supplementation on Plasma Lipids in Humans: A Systematic Review and Meta-Analysis of Clinical Trials, Phytotherapy Research (2019)
17. Comparison Between European and Iranian Cutoff Points of Triglyceride/High-Density Lipoprotein Cholesterol Concentrations in Predicting Cardiovascular Disease Outcomes, Journal of Clinical Lipidology (2016)
18. Cardiovascular Disease Risk Factors, Metabolic Syndrome and Obesity in an Iranian Population, Eastern Mediterranean Health Journal (2008)
19. Low-Density Lipoprotein Cholesterol and Metabolic Syndrome in an Iranian High-Risk Population, Diabetes and Metabolic Syndrome: Clinical Research and Reviews (2015)
20. Lipid Profiles in the Isfahan Population: An Isfahan Cardiovascular Disease Risk Factor Survey, 1994, Eastern Mediterranean Health Journal (1999)
21. Lipid Profile Cutoff Values for Predicting Hypertension in an Iranian Population (Roc Curve Analysis), Medical Science Monitor (2007)
22. Dietary Choline and Betaine Intake, Cardio-Metabolic Risk Factors and Prevalence of Metabolic Syndrome Among Overweight and Obese Adults, BMC Endocrine Disorders (2023)
23. Comparison of Effects of Soft Margarine, Blended, Ghee, and Unhydrogenated Oil With Hydrogenated Oil on Serum Lipids: A Randomized Clinical Trail, ARYA Atherosclerosis (2013)
24. The Effects of Conjugated Linoleic Acid Supplementation on Lipid Profile in Adults: A Systematic Review and Dose–Response Meta-Analysis, Frontiers in Nutrition (2022)
25. Is Family History of Premature Cardiovascular Diseases Appropriate for Detection of Dyslipidemic Children in Population-Based Preventive Medicine Programs? Caspian Study, Pediatric Cardiology (2006)
26. Assessing Body Shape Index As a Risk Predictor for Cardiovascular Diseases and Metabolic Syndrome Among Iranian Adults, Nutrition (2014)
27. The Effects of Isolated Soy Protein, Isolated Soy Isoflavones and Soy Protein Containing Isoflavones on Serum Lipids in Postmenopausal Women: A Systematic Review and Meta-Analysis, Critical Reviews in Food Science and Nutrition (2020)
28. Cardiovascular Disease Risk Assessment: Triglyceride/High-Density Lipoprotein Versus Metabolic Syndrome Criteria, Journal of Research in Health Sciences (2019)
29. Consumption of Energy-Dense Diets in Relation to Cardiometabolic Abnormalities Among Iranian Women, Public Health Nutrition (2012)
30. Dietary Patterns in Relation to Lipid Profiles Among Iranian Adults, Journal of Cardiovascular and Thoracic Research (2019)
31. First Report on the Validity of a Continuous Metabolic Syndrome Score As an Indicator for Metabolic Syndrome in a National Sample of Paediatric Population - the Caspian-Iii Study, Endokrynologia Polska (2013)
32. Inverse Association of Legume Consumption and Dyslipidemia: Isfahan Healthy Heart Program, Journal of Clinical Lipidology (2014)
33. First Nationwide Study of the Prevalence of the Metabolic Syndrome and Optimal Cutoff Points of Waist Circumference in the Middle East: The National Survey of Risk Factors for Noncommunicable Diseases of Iran, Diabetes Care (2009)
34. Effects of Two Types of Moderate-And High-Intensity Interval Training on Serum Salusin-Α and Salusin-Β Levels and Lipid Profile in Women With Overweight/Obesity, Diabetes, Metabolic Syndrome and Obesity (2020)
35. Soy Inclusion in the Diet Improves Features of the Metabolic Syndrome: A Randomized Cross-Over Study in Postmenopausal Women, Iranian Journal of Diabetes and Lipid Disorders (2007)
36. The Effect of Glucomannan Supplementation on Lipid Profile in Adults: A Grade-Assessed Systematic Review and Meta-Analysis, BMC Cardiovascular Disorders (2024)
37. Associations Between Serum Ceruloplasmin Level, Obesity and Metabolic and Inflammatory Indexes, Journal of Isfahan Medical School (2012)
38. Triglyceride Glucose-Waist Circumference As a Predictor of Mortality and Subtypes of Cardiovascular Disease: A Systematic Review and Meta-Analysis, Diabetology and Metabolic Syndrome (2025)
39. Association Between Plant and Animal Proteins Intake With Lipid Profile and Anthropometric Indices: A Cross-Sectional Study, Nutrition and Health (2024)
40. A Priority Oriented Nutrition Education Program to Improve Nutritional and Cardiometabolic Status in the Workplace: A Randomized Field Trial, Journal of Occupational Medicine and Toxicology (2020)
41. Lipids and Diastolic Dysfunction: Recent Evidence and Findings, Nutrition, Metabolism and Cardiovascular Diseases (2022)
42. Association Between Vitamin D Status and Lipid Profile in Children and Adolescents: A Systematic Review and Meta-Analysis, International Journal of Food Sciences and Nutrition (2014)
43. Association of Dietary Pattern and Metabolic Syndrome in 15- to 49-Years-Old Women, Journal of Isfahan Medical School (2015)
44. Is Any Association Between Alternate Healthy Eating Index (Ahei) With Lipid Profile and Liver Enzymes? a Cross-Sectional Study, Journal of Diabetes and Metabolic Disorders (2021)
45. The Effects of Magnesium Supplementation on Lipid Profile Among Type 2 Diabetes Patients: A Systematic Review and Meta-Analysis of Randomized Controlled Trials, Biological Trace Element Research (2021)
46. Lipid Variability and Risk of Microvascular Complications in Patients With Diabetes: A Systematic Review and Meta-Analysis, BMC Endocrine Disorders (2024)
47. Interaction Between Dietary Total Antioxidant Capacity and Bdnf Val66met Polymorphism on Lipid Profiles and Atherogenic Indices Among Diabetic Patients, Scientific Reports (2021)
48. Effect of High Protein Diet on Cardiovascular Disease Risk Factors, Journal of Isfahan Medical School (2012)
49. Changes in Serum Lipid Profile of Obese or Overweight Children and Adolescents Following a Lifestyle Modification Course, ARYA Atherosclerosis (2012)
50. Does Alpha-Lipoic Acid Affect Lipid Profile? a Meta-Analysis and Systematic Review on Randomized Controlled Trials, European Journal of Pharmacology (2019)