Isfahan University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
Glycemic Index, Glycemic Load, and Common Psychological Disorders Publisher Pubmed



Haghighatdoost F1, 2 ; Azadbakht L1, 2, 5 ; Keshteli AH6 ; Feinlebisset C7 ; Daghaghzadeh H3 ; Afshar H3 ; Feizi A4 ; Esmaillzadeh A1 ; Adibi P3
Authors
Show Affiliations
Authors Affiliations
  1. 1. Food Security Research Center, School of Nutrition and Food Science, Ireland
  2. 2. Department of Community Nutrition, School of Nutrition and Food Science, United States
  3. 3. Integrative Functional Gastroenterology Research Center, United States
  4. 4. Biostatistics and Epidemiology Department, School of Health, Isfahan University of Medical Sciences, Isfahan, Iran
  5. 5. Department of Community Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran
  6. 6. Department of Medicine, University of Alberta, Edmonton, Canada
  7. 7. University of Adelaide Discipline of Medicine and National Health, Med. Res. Council Centre of Research Excellence of Translating Nutritional Science to Good Health, Adelaide, Australia

Source: American Journal of Clinical Nutrition Published:2016


Abstract

Background: Potential associations between dietary glycemic index (GI) and glycemic load (GL) with psychological disorders remain uncertain. Objective: We investigated the relations of dietary GI and GL with psychological distress, anxiety, and depression. Design: A total of 3363 nonacademic members of the staff of Isfahan University of Medical Sciences were included in this cross-sectional study. GI and GL were assessed by using a validated, self-administered, dish-based, semiquantitative food-frequency questionnaire. Validated Iranian versions of the Hospital Anxiety and Depression Scale and General Health Questionnaire-12 were used to assess anxiety, depression, and psychological distress. Results: After control for potential confounders, individuals in the top tertile of GI had greater odds of depression (OR: 1.44; 95% CI: 1.03, 2.02; P-trend = 0.03) and a trend for greater odds of anxiety (OR: 1.52; 95% CI: 0.97, 2.38; Ptrend = 0.06) compared with those in the first tertile. Higher GL values were linked to lower odds for mental disorders (OR: 0.66; 95% CI: 0.49, 0.90; P-trend = 0.009), depression (OR: 0.69; 95% CI: 0.51, 0.93; P-trend = 0.02), and psychological distress (OR: 0.67; 95% CI: 0.48, 0.92; P-trend = 0.01). Significant interactions were observed between GI and sex for depression (P = 0.01) and psychological distress (P = 0.046) in the crude model. In stratified analyses by sex, after control for potential confounders, a greater GI was linked to a higher odds of depression (OR: 1.52; 95% CI: 1.20, 1.94; P-trend = 0.001) and psychological distress (OR: 1.66; 95% CI: 1.28, 2.14; P-trend = 0.001) in women but not in men. Conclusion: Our findings support a direct link between the odds of depression and dietary GI but inverse associations between GL and mental disorders, depression, and psychological distress. © 2016 American Society for Nutrition.
Related Docs
View other Related Docs
1. The Association of Whole and Refined Grains Consumption With Psychological Disorders Among Iranian Adults, European Journal of Nutrition (2019)
2. Adherence to Mediterranean Dietary Pattern Is Inversely Associated With Depression, Anxiety and Psychological Distress, Nutritional Neuroscience (2021)
3. Higher Dietary Glycemic Load Is Inversely Associated With Stress Prevalence Among Iranian Adults, BMC Neuroscience (2022)
4. Glycemic Index, Glycemic Load, and Depression: A Systematic Review and Meta-Analysis, European Journal of Clinical Nutrition (2019)
5. Association Between Dietary Insulin Index and Load and Psychological Disorders, British Journal of Nutrition (2020)
6. Legume and Nut Consumption in Relation to Depression, Anxiety and Psychological Distress in Iranian Adults, European Journal of Nutrition (2020)
7. The Association Between Dietary Intake of Magnesium and Psychiatric Disorders Among Iranian Adults: A Cross-Sectional Study, British Journal of Nutrition (2018)
8. Dietary Treatment Options for Depression Among Diabetic Patient, Focusing on Macronutrients, Journal of Diabetes Research (2013)
Experts (# of related papers)
View all Related Experts
Peyman Adibi (99)
Hamid Afshar Zanjani (57)
Other Related Docs
9. Empirically Derived Dietary Patterns in Relation to Psychological Disorders, Public Health Nutrition (2016)
10. Association of Dietary Phytochemical Index and Mental Health in Women: A Cross-Sectional Study, British Journal of Nutrition (2019)
11. Empirically Derived Food-Based Dietary Inflammatory Index Is Associated With Increased Risk of Psychological Disorders in Women, Nutritional Neuroscience (2021)
12. The Association Between Dietary Insulin Index and Load With Mental Health, BMC Psychology (2022)
13. Association Between the Dietary Inflammatory Index and Common Mental Health Disorders Profile Scores, Clinical Nutrition (2019)
14. The Association of Dietary Macronutrient Quality Indices With Depression and Anxiety Symptoms and Quality of Life in Iranian Adults: The Lipokap Study, Journal of Affective Disorders (2022)
15. Adherence to the Dash Diet in Relation to Psychological Profile of Iranian Adults, European Journal of Nutrition (2017)
16. The Relationship Between a Plant-Based Diet and Mental Health: Evidence From a Cross-Sectional Multicentric Community Trial (Lipokap Study), PLoS ONE (2023)
17. Dietary Patterns in Relation With Psychosomatic Complaints Profile: Results From Sepahan Study Among a Large Sample of General Adults, Nutritional Neuroscience (2020)
18. Red and White Meat Intake in Relation to Mental Disorders in Iranian Adults, Frontiers in Nutrition (2021)
19. The Association Between Dietary Glycemic Index, Glycemic Load and Diet Quality Indices in Iranian Adults: Results From Isfahan Healthy Heart Program, International Journal of Food Sciences and Nutrition (2016)
20. Adherence to Alternative Healthy Eating Index in Relation to Depression and Anxiety in Iranian Adults, British Journal of Nutrition (2016)
21. The Mind (Mediterranean-Dash Diet Intervention for Neurodegenerative Delay) and Mediterranean Diets Are Differently Associated With Psychosomatic Complaints Profile in Adults: Results From Sepahan Cross-Sectional Study, Mediterranean Journal of Nutrition and Metabolism (2020)
22. Psychological Disorders and Dietary Patterns by Reduced-Rank Regression, European Journal of Clinical Nutrition (2019)
23. Association Between Dietary Inflammatory Index and Psychological Profile in Adults, Clinical Nutrition (2019)
24. Dietary Glycemic Index and Glycemic Load in Relation to General Obesity and Central Adiposity Among Adults, Clinical Nutrition (2019)
25. Consumption of Fruit and Vegetables in Relation With Psychological Disorders in Iranian Adults, European Journal of Nutrition (2018)
26. Association Between Dietary Glycemic Index and Glycemic Load and Glioma: A Case-Control Study, Nutritional Neuroscience (2022)
27. Combined Healthy Lifestyle Is Inversely Associated With Psychological Disorders Among Adults, PLoS ONE (2016)
28. Dietary Intake of Branched-Chain Amino Acids in Relation to Depression, Anxiety and Psychological Distress, Nutrition Journal (2021)
29. The Association of Ultra-Processed Food Consumption With Adult Mental Health Disorders: A Systematic Review and Dose-Response Meta-Analysis of 260,385 Participants, Nutritional Neuroscience (2023)
30. The Association of Legume Consumption and Psychological Health Among Women: A Cross-Sectional Study, Journal of Nutrition and Food Security (2021)
31. Dietary Acid Load in Relation to Depression and Anxiety in Adults, Journal of Human Nutrition and Dietetics (2020)
32. The Association of Plant-Based Dietary Patterns and Psychological Disorders Among Iranian Adults, Journal of Affective Disorders (2022)
33. Breakfast Skipping Alone and in Interaction With Inflammatory Based Quality of Diet Increases the Risk of Higher Scores of Psychological Problems Profile in a Large Sample of Iranian Adults, Journal of Nutritional Science (2021)
34. The Association of Potato Consumption and Psychological Disorders in Women: A Cross-Sectional Study, Journal of Nutrition and Food Security (2020)
35. Consumption of Dietary Fiber in Relation to Psychological Disorders in Adults, Frontiers in Psychiatry (2021)
36. Total Fat and Omega-3 Fatty Acids Intake in Relation to Serum Brain-Derived Neurotrophic Factor (Bdnf) Levels and Psychological Disorders in Iranian Adults, Scientific Reports (2023)
37. Dietary Riboflavin Intake in Relation to Psychological Disorders in Iranian Adults: An Observational Study, Scientific Reports (2023)
38. Adherence to the Mind Diet and Prevalence of Psychological Disorders in Adults, Journal of Affective Disorders (2019)
39. The Relationship Between Linoleic Acid Intake and Psychological Disorders in Adults, Frontiers in Nutrition (2022)
40. The Association of Food Quality Index With Mental Health in Women: A Cross-Sectional Study, BMC Research Notes (2020)
41. Dietary Total Antioxidant Capacity in Relation to Depression and Anxiety in Iranian Adults, Nutrition (2019)
42. Dietary Glycemic Index and Glycemic Load in Association With Sleep Duration: Yahs-Tamyz and Shahedieh Observational Studies, Clinical Nutrition ESPEN (2021)
43. Dietary Glycemic Index and Insulin Index in Association With Incident Type 2 Diabetes Mellitus in Adults, British Journal of Nutrition (2025)
44. Dietary Methyl Donor Micronutrients Intake in Relation to Psychological Disorders in Adults, British Journal of Nutrition (2022)
45. Are Dietary Patterns Differently Associated With Differentiated Levels of Mental Health Problems? Results From a Large Cross-Sectional Study Among Iranian Manufacturing Employees, BMJ Open (2019)
46. Egg Consumption and Prevalence of Psychological Disorders in Adults, European Journal of Nutrition (2019)
47. The Association of Red Meat Consumption and Mental Health in Women: A Cross-Sectional Study, Complementary Therapies in Medicine (2021)
48. Healthy and Unhealthy Dietary Patterns Are Related to Depression: A Case-Control Study, Psychiatry Investigation (2015)
49. Do Patterns of Nutrient Intake Predict Self-Reported Anxiety, Depression and Psychological Distress in Adults? Sepahan Study, Clinical Nutrition (2019)
50. A Body Shape Index and Body Roundness Index in Relation to Anxiety, Depression, and Psychological Distress in Adults, Frontiers in Nutrition (2022)