Isfahan University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
The Association Between Dietary Intake of Magnesium and Psychiatric Disorders Among Iranian Adults: A Cross-Sectional Study Publisher Pubmed



Anjomshoae J1, 2 ; Sadeghi O1, 2 ; Hassanzadeh Keshteli A3 ; Afshar H4 ; Esmaillzadeh A2, 5, 6 ; Adibi P7
Authors
Show Affiliations
Authors Affiliations
  1. 1. Studs. Scientific Center, Tehran University of Medical Sciences, PO Box 1417755331, Tehran, Iran
  2. 2. Department of Community Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, PO Box 141556117, Tehran, Iran
  3. 3. Department of Medicine, University of Alberta, PO Box 7-142, Edmonton, AB, Canada
  4. 4. Psychosomatic Research Center, Isfahan University of Medical Sciences, PO Box 81745-151, Isfahan, Iran
  5. 5. Obesity and Eating Habits Research Center, Endocrinology and Metabolism Molecular-Cellular Sciences Institute, Tehran University of Medical Sciences, PO Box 1414413137, Tehran, Iran
  6. 6. Department of Community Nutrition, School of Nutrition and Food Science, Isfahan University of Medical Sciences, PO Box 8174673461, Isfahan, Iran
  7. 7. Integrative Functional Gastroenterology Research Center, Isfahan University of Medical Sciences, PO Box 81745-151, Isfahan, Iran

Source: British Journal of Nutrition Published:2018


Abstract

Findings from clinical trials on the effect of Mg supplementation on depression and anxiety are not generalisable to the community owing to high-dose intervention in short-term periods. Limited observational data are available linking dietary intake of Mg and psychiatric disorders. We aimed to investigate the association between dietary intake of Mg and psychiatric disorders in a large cross-sectional study on Iranian adults. A total of 3172 Iranian adults (with an age range of 18-55 years) were included in this study. Data on dietary intakes were collected using a validated dish-based 106-item semi-quantitative FFQ. To assess depression and anxiety, an Iranian validated version of the Hospital Anxiety and Depression Scale was used. Furthermore, psychological distress was examined using the General Health Questionnaire. The mean age of men and women was 38·4 (sd 8·2) and 35·1 (sd 7·4) years, respectively. In unadjusted analyses, we found that higher dietary Mg intake was associated with lower odds of anxiety among women (OR 0·61; 95 % CI 0·41, 0·90), such that after taking potential confounders into account women in the highest quintile of Mg intake had a 39 % lower odds of anxiety compared with those in the lowest quintile (OR 0·61; 95 % CI 0·40, 0·93). Moreover, deficient Mg intake was positively associated with anxiety among all women (OR 1·80; 95 % CI 1·19, 2·72) and also normal-weight women (OR 1·73; 95 % CI 1·01, 2·95). In addition, a significant inverse association was found between dietary Mg intake and depression among normal-weight men (OR 0·45; 95 % CI 0·20, 0·99) and overweight women (OR 0·45; 95 % CI 0·24, 0·85). In conclusion, dietary intake of Mg was inversely associated with depression and anxiety. However, such findings were not seen for psychological distress. © The Authors 2018.
Related Docs
View other Related Docs
1. Legume and Nut Consumption in Relation to Depression, Anxiety and Psychological Distress in Iranian Adults, European Journal of Nutrition (2020)
2. The Association of Whole and Refined Grains Consumption With Psychological Disorders Among Iranian Adults, European Journal of Nutrition (2019)
3. Adherence to Mediterranean Dietary Pattern Is Inversely Associated With Depression, Anxiety and Psychological Distress, Nutritional Neuroscience (2021)
4. Association of Dietary Acid-Base Load and Psychological Disorders Among Iranian Women: A Cross-Sectional Study, Complementary Therapies in Medicine (2020)
5. Dietary Methyl Donor Micronutrients Intake in Relation to Psychological Disorders in Adults, British Journal of Nutrition (2022)
6. Associations Between Dietary Intake of B-Vitamins and Psychological Disorders Among Iranian Women: A Cross-Sectional Study, Public Health Nutrition (2021)
7. Dietary Magnesium Intake in Relation to Depression in Adults: A Grade-Assessed Systematic Review and Dose-Response Meta-Analysis of Epidemiologic Studies, Nutrition Reviews (2025)
8. Dietary Riboflavin Intake in Relation to Psychological Disorders in Iranian Adults: An Observational Study, Scientific Reports (2023)
Experts (# of related papers)
View all Related Experts
Peyman Adibi (87)
Hamid Afshar Zanjani (52)
Other Related Docs
9. The Relationship Between Linoleic Acid Intake and Psychological Disorders in Adults, Frontiers in Nutrition (2022)
10. Glycemic Index, Glycemic Load, and Common Psychological Disorders, American Journal of Clinical Nutrition (2016)
11. Association Between Dietary Insulin Index and Load and Psychological Disorders, British Journal of Nutrition (2020)
12. Empirically Derived Food-Based Dietary Inflammatory Index Is Associated With Increased Risk of Psychological Disorders in Women, Nutritional Neuroscience (2021)
13. Adherence to the Mind Diet and Prevalence of Psychological Disorders in Adults, Journal of Affective Disorders (2019)
14. The Association of Food Quality Index With Mental Health in Women: A Cross-Sectional Study, BMC Research Notes (2020)
15. Association of Dietary Phytochemical Index and Mental Health in Women: A Cross-Sectional Study, British Journal of Nutrition (2019)
16. Adherence to the Dash Diet in Relation to Psychological Profile of Iranian Adults, European Journal of Nutrition (2017)
17. Consumption of Fruit and Vegetables in Relation With Psychological Disorders in Iranian Adults, European Journal of Nutrition (2018)
18. Dietary Total Antioxidant Capacity in Relation to Depression and Anxiety in Iranian Adults, Nutrition (2019)
19. Association Between Dietary Inflammatory Index and Psychological Profile in Adults, Clinical Nutrition (2019)
20. Dietary Acid Load in Relation to Depression and Anxiety in Adults, Journal of Human Nutrition and Dietetics (2020)
21. The Association of Plant-Based Dietary Patterns and Psychological Disorders Among Iranian Adults, Journal of Affective Disorders (2022)
22. Consumption of Dietary Fiber in Relation to Psychological Disorders in Adults, Frontiers in Psychiatry (2021)
23. The Mind (Mediterranean-Dash Diet Intervention for Neurodegenerative Delay) and Mediterranean Diets Are Differently Associated With Psychosomatic Complaints Profile in Adults: Results From Sepahan Cross-Sectional Study, Mediterranean Journal of Nutrition and Metabolism (2020)
24. Psychological Disorders and Dietary Patterns by Reduced-Rank Regression, European Journal of Clinical Nutrition (2019)
25. The Relationship Between a Plant-Based Diet and Mental Health: Evidence From a Cross-Sectional Multicentric Community Trial (Lipokap Study), PLoS ONE (2023)
26. Higher Vitamin B6intake Is Associated With Lower Depression and Anxiety Risk in Women But Not in Men: A Large Cross-Sectional Study, International Journal for Vitamin and Nutrition Research (2020)
27. Empirically Derived Dietary Patterns in Relation to Psychological Disorders, Public Health Nutrition (2016)
28. The Association of Legume Consumption and Psychological Health Among Women: A Cross-Sectional Study, Journal of Nutrition and Food Security (2021)
29. Dietary Intake of Branched-Chain Amino Acids in Relation to Depression, Anxiety and Psychological Distress, Nutrition Journal (2021)
30. Do Patterns of Nutrient Intake Predict Self-Reported Anxiety, Depression and Psychological Distress in Adults? Sepahan Study, Clinical Nutrition (2019)
31. Adherence to Alternative Healthy Eating Index in Relation to Depression and Anxiety in Iranian Adults, British Journal of Nutrition (2016)
32. A Dish-Based Semi-Quantitative Food Frequency Questionnaire for Assessment of Dietary Intakes in Epidemiologic Studies in Iran: Design and Development, International Journal of Preventive Medicine (2014)
33. Association Between the Dietary Inflammatory Index and Common Mental Health Disorders Profile Scores, Clinical Nutrition (2019)
34. Egg Consumption and Prevalence of Psychological Disorders in Adults, European Journal of Nutrition (2019)
35. Combined Healthy Lifestyle Is Inversely Associated With Psychological Disorders Among Adults, PLoS ONE (2016)
36. Red and White Meat Intake in Relation to Mental Disorders in Iranian Adults, Frontiers in Nutrition (2021)
37. Adherence to Low Carbohydrate Diet and Prevalence of Psychological Disorders in Adults, Nutrition Journal (2019)
38. Coffee and Caffeine Intake in Relation to Symptoms of Psychological Disorders Among Adults, Public Health Nutrition (2022)
39. Can Following Paleolithic and Mediterranean Diets Reduce the Risk of Stress, Anxiety, and Depression: A Cross-Sectional Study on Iranian Women, Journal of Nutrition and Metabolism (2023)
40. Total Fat and Omega-3 Fatty Acids Intake in Relation to Serum Brain-Derived Neurotrophic Factor (Bdnf) Levels and Psychological Disorders in Iranian Adults, Scientific Reports (2023)
41. Nutrient Patterns and Their Relation to General and Abdominal Obesity in Iranian Adults: Findings From the Sepahan Study, European Journal of Nutrition (2016)
42. Breakfast Consumption in Relation to Lowered Risk of Psychological Disorders Among Iranian Adults, Public Health (2019)
43. Substituting Whole Grains for Refined Grains and Risk of Developing Psychological Disorders in Iranian Adults: Yahs and Tamyz Studies, Current Psychology (2023)
44. A Body Shape Index and Body Roundness Index in Relation to Anxiety, Depression, and Psychological Distress in Adults, Frontiers in Nutrition (2022)
45. Dietary Patterns and Prevalence of Irritable Bowel Syndrome in Iranian Adults, Neurogastroenterology and Motility (2016)
46. The Association of the Prime Diet Quality Score (Pdqs) With Depression and Anxiety Symptoms: The Isfahan Functional Disorders (Isfun) Cohort Study, Nutritional Neuroscience (2025)
47. The Association of Red Meat Consumption and Mental Health in Women: A Cross-Sectional Study, Complementary Therapies in Medicine (2021)
48. Dietary Phytochemical Index in Relation to Risk of Glioma: A Case-Control Study in Iranian Adults, Nutrition Journal (2021)
49. The Prevalence of Depression and Anxiety and Their Lifestyle Determinants in a Large Sample of Iranian Adults: Results From a Population Based Cross-Sectional Study; [Prevalencija Depresije I Anksioznosti I Njihovih Determinanti Zivota U Velikom Uzorku Iranaca: Rezultati Studije Preseka], Serbian Journal of Experimental and Clinical Research (2020)
50. Magnesium Supplementation Beneficially Affects Depression in Adults With Depressive Disorder: A Systematic Review and Meta-Analysis of Randomized Clinical Trials, Frontiers in Psychiatry (2023)