Determination of Streptococcus Sanguis in Gingivitis Disease and Effect of Β-Lactam Antibiotics on It



Kermanshahi RK¹ ; Ghalayani P² ; Zargarzadeh MR³ Show Affiliations
Source: Journal of Isfahan Medical School Published:2010

Abstract

Background: Gingivitis is a destructive inflammatory disease. The results of some studies show that bacteria of plaques are different in diseased and healthy areas; so the identification and sensitivity to β-lactam antibiotics was the most important aim of this study. Methods: This study was performed on 361 strains of bacteria identified by biochemical tests; the number of streptococcus and its percentage were 204 and 55.9 respectively. The antimicrobial susceptibility of strains of streptococcus was determined by Disk plate or Kerby - Bauer. The difference between the mean zones of inhibition of gingivitis strains were studied by t-test. Findings: The percentages of streptococcus sanguis was 26.4% and of streptococcus sanguis more than 70%. These bacteria were sensitive to amoxicillin, co-amoxiclave, and erythromycin and also sensitive to tetracycline, penicillin, and cephalexin. 1% of these bacteria were sensitive to clindamyc. Conclusion: These bacteria were sensitive to β-lactam antibiotics, and we can use β-lactam antibiotics for treatment.