Isfahan University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
Opium Addiction and Ischemic Stroke in Isfahan, Iran: A Case-Control Study Publisher Pubmed



Ebrahimi H1 ; Haghjoo Javanmard S2 ; Asgary S2 ; Dehghani L3 ; Amiri M4 ; Saadatnia M5
Authors
Show Affiliations
Authors Affiliations
  1. 1. School of Medicine, Islamic Azad University, Najafabad Branch, Isfahan, Iran
  2. 2. Department of Physiology, Applied Physiology Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
  3. 3. Department of Tissue Engineering and Regenerative Medicine, School of Advanced Technologies in Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  4. 4. Social Health Determinants Research Center and Department of Epidemiology and Biostatistics, School of Health, Shahrekord University of Medical Sciences, Shahrekord, Iran
  5. 5. Isfahan Neurosciences Research Center, Alzahra Research Institute, Department of Neurology, Isfahan University of Medical Sciences, Isfahan, 8174673461, Iran

Source: European Neurology Published:2018


Abstract

Background: The effect of opium addiction (OA) on cerebrovascular disease is controversial. The aim of this study was to clarify this relationship in Iranian patients with ischemic stroke. Methods: In a case-control study, 672 patients with ischemic stroke and 293 controls without a previous history of cerebrovascular or cardiovascular diseases were compared. OA as well as other risk factors such as diabetes mellitus (DM), hypertension (HTN), hyperlipidemia, tobacco smoking (TS) were compared between the 2 groups. Results: OA percentage, TS, TS amount (pack/year), HTN and DM history were significantly higher in the case group compared to controls (p < 0.05). After regression analysis between risk factors, a significant difference remained between 2 groups with regards to HTN (OR 4.21, 95% CI 3.05-5.81, p < 0.001), TS (OR 2.33, 95% CI 1.51-3.59, p < 0.001), and OA (OR 2.36, 95% CI 1.16-4.85, p = 0.018). Conclusion: Our study showed OA is a risk factor for stroke. However, a follow-up study with a larger cohort is required to confirm the results. © 2017 S. Karger AG, Basel. Copyright: All rights reserved.
Related Docs
View other Related Docs
1. The Relationship of Opium Addiction With Coronary Artery Disease, International Journal of Preventive Medicine (2010)
2. Does Opium Consumption Have Shared Impact on Atherosclerotic Cardiovascular Disease and Cancer?, Archives of Iranian Medicine (2022)
3. Effects of Opium Consumption on Cardiometabolic Diseases, Nature Reviews Cardiology (2013)
4. Effect of Opium Addiction on New and Traditional Cardiovascular Risk Factors: Do Duration of Addiction and Route of Administration Matter?, Lipids in Health and Disease (2008)
5. Effects of Opium Addiction on Vascular Endothelium, Journal of Isfahan Medical School (2013)
6. Opioid Use Disorder and Intracerebral Hemorrhage in Isfahan, Iran: A Case–Control Study, Frontiers in Neurology (2024)
7. Long-Term Effects of Opium Consumption Following Percutaneous Coronary Intervention: A 10-Year Follow-Up Study, Global Heart (2024)
8. Prevalence of Delirium in Opium Users After Coronary Artery Bypass Graft Surgery, International Journal of Preventive Medicine (2014)
Experts (# of related papers)
View all Related Experts
Mohammad Saadatnia (15)
Nizal Sarrafzadegan (6)
Other Related Docs
9. Opium Decreases the Age at Myocardial Infarction and Sudden Cardiac Death: A Long-And Short-Term Outcome Evaluation, Archives of Iranian Medicine (2013)
10. Epidemiologic Evaluation and Seasonal Variations of Stroke Risk Factors Among Patients With First and Recurrent Stroke, Journal of Isfahan Medical School (2012)
11. Risk Factors for Opioids and Stimulants Poisoning Among Patients Admitted to Khorshid Hospital in Isfahan, Journal of Isfahan Medical School (2022)
12. Investigating the Relation of Drug Abusing and Oral Health in Addicts, Journal of Isfahan Medical School (2015)
13. Lifetime Prevalence and Correlates of Smoking Behavior in Iranian Adults' Population; a Cross-Sectional Study, BMC Public Health (2019)
14. Consumption of Sugar-Sweetened Beverages in Relation to Stroke: A Case-Control Study, International Journal of Food Sciences and Nutrition (2013)
15. Effect of Opium Versus Methadone on Polysomnographic Characteristics of Patients With Obesity Hypoventilation Syndrome, Basic and Clinical Neuroscience (2024)
16. Neuromuscular Manifestations of Lead Poisoning in Opium and Herbal Users in Iran, Revue Neurologique (2020)
17. Evaluation of the Neuroprotective Effect of Dextromethorphan in the Acute Phase of Ischaemic Stroke, Archives of Medical Science (2011)
18. Opium Consumption and Risk of Liver Fibrosis in Chronic Hepatitis B and C, Journal of Isfahan Medical School (2010)
19. Difference Between Risk Factors of Anterior and Posterior Circulation Strokes, Journal of Research in Medical Sciences (2007)
20. Cannabis and Opium Abuse Patterns and Their Associated Complications in a Sample of Young Iranians, Journal of Child and Adolescent Substance Abuse (2012)
21. Variations in Risks From Smoking Between High-Income, Middle-Income, and Low-Income Countries: An Analysis of Data From 179 000 Participants From 63 Countries, The Lancet Global Health (2022)
22. Blood Lead Level in Opium Dependents and Its Association With Anemia: A Cross-Sectional Study From the Capital of Iran, Journal of Research in Medical Sciences (2014)
23. Public Stroke Knowledge, Awareness, and Response to Acute Stroke in Isfahan Iran: What Is Less or Misinterpreted in Developing Countries, Journal of Stroke and Cerebrovascular Diseases (2021)
24. Epidemiologic Evaluation of Stroke Risk Factors Among Rural-Urban Patients in Isfahan University Hospitals, Iran, Journal of Isfahan Medical School (2012)
25. A Case-Control Study on Potato Consumption and Risk of Stroke in Central Iran, Archives of Iranian Medicine (2013)
26. The Effect of Perphenazine Add-On Therapy to Matrix Intervention on Control of Craving and Relapse in Methamphetamine Users: A Randomized Controlled Trial, International Journal of High Risk Behaviors and Addiction (2022)
27. Relation of Stroke Risk Factors With Specific Stroke Subtypes and Territories, Iranian Journal of Public Health (2015)
28. Opium Use and Cancer Risk: A Comprehensive Systematic Review and Meta-Analysis of Observational Studies, International journal of clinical practice (2022)
29. Dietary Total Antioxidant Capacity in Relation to Stroke Among Iranian Adults, Nutritional Neuroscience (2020)
30. Is Opium Addiction a Risk Factor for Deep Vein Thrombosis? a Case-Control Study, Blood Coagulation and Fibrinolysis (2010)
31. Ischemic Stroke in Young Asian Women: Risk Factors, Subtypes and Outcome, Cerebrovascular Diseases (2010)
32. Opium and Tobacco Use, and Outcome in Covid-19 Infected Patients: A Cross-Sectional Study, International Journal of High Risk Behaviors and Addiction (2024)
33. The Effect of Opium on Polysomnographic Findings in Patients With Sleep Apnea, Tanaffos (2010)
34. Examining the Frequency of Clinical and Paraclinical Symptoms in Opium Addicts Hospitalized Due to Lead Poisoning in Isfahan Province, Advanced Biomedical Research (2025)
35. Oral Health-Related Quality of Life Among a Group of Patients With Substance Use Disorders in Rehabilitation Treatment: A Cross-Sectional Study, BMC Oral Health (2021)
36. Prevalence of Substance Abuse and Its Association With Cigarette Smoking in Isfahan University of Medical Sciences Students in 2013, Koomesh (2015)
37. Lipid Profile in Patients With Ischemic and Hemorrhagic Stroke, Journal of Isfahan Medical School (2011)
38. Dietary Phytochemical Index in Relation to Risk of Stroke: A Case-Control Study, Nutritional Neuroscience (2022)
39. The Effect of Statin Therapy in Stroke Outcome: A Double Blind Clinical Trial, International Journal of Preventive Medicine (2012)
40. Effect of Opium Addiction on Lipid Profile and Atherosclerosis Among Normal and Hypercholesterolemic Rabbits, Iranian Journal of Diabetes and Lipid Disorders (2007)
41. Metabolic Syndrome and the Risk of Ischemic Stroke, Journal of Stroke and Cerebrovascular Diseases (2017)
42. A Hospital-Based Case-Control Study on Whole-And Refined-Grain Intake and Risk of Stroke, ARYA Atherosclerosis (2023)
43. Coronary Angiogenesis During Morphine and Nicotine Withdrawal in Two-Kidney One Clip Hypertensive (2K1c) Rats, Bratislava Medical Journal (2015)
44. Morphine and Nicotine Addiction and Withdrawal Influence Baroreflex Sensitivity and Blood Pressure in Two-Kidney One Clip Hypertensive (2K1c) Rats, Bratislava Medical Journal (2014)
45. Central Serous Chorioretinopathy Risk Factors in an Iranian Cohort: A Case-Control Study, Journal of Ophthalmic and Vision Research (2023)
46. Dietary Patterns in Relation to Stroke Among Iranians: A Case-Control Study, Journal of the American College of Nutrition (2015)
47. The Impact of Health-Related Quality of Life on the Incidence of Ischaemic Heart Disease and Stroke; a Cohort Study in an Iranian Population, Acta Cardiologica (2016)
48. Effect of Opium Addiction on Lipid Profile and Atherosclerosis Formation in Hypercholesterolemic Rabbits, Experimental and Toxicologic Pathology (2009)
49. Risk Factors of Atherosclerosis in Male Smokers, Passive Smokers, and Hypertensive Nonsmokers in Central Iran, ARYA Atherosclerosis (2012)
50. Burden of Drug and Alcohol Use Disorders in Iran: Findings From the Global Burden of Disease Study 2010, Archives of Iranian Medicine (2015)