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Retroperitoneal Hematoma in Patients With Covid-19 Infection During Anticoagulant Therapy: A Case Series and Literature Review Publisher Pubmed



Hashemi H1 ; Moradi H2 ; Hashemi M1 ; Naderi Z1 ; Jafarpisheh S3
Authors
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Authors Affiliations
  1. 1. Department of Internal Medicine, Isfahan University of Medical Science, Isfahan, Iran
  2. 2. Isfahan Students Research Committee, Medical School, Isfahan University of Medical Science, Isfahan, Iran
  3. 3. Department of Radiology, Isfahan University of Medical Sciences, Isfahan, Iran

Source: Journal of International Medical Research Published:2022


Abstract

Due to the hypercoagulable status of patients with severe COVID-19 infection, anticoagulants are often used to prevent thrombosis. However, these agents may cause bleeding events such as retroperitoneal hematoma (RPH). We report here on six patients with COVID-19 who developed RPH during treatment. Early evidence of bleeding led to confirmatory diagnosis with imaging. Four patients recovered with supportive treatment (IV fluids and blood transfusions) and two patients recovered by angioembolization. RPH should be considered in COVID patients on anticoagulants as soon as haemoglobin or blood pressure falls. Further studies are required to provide guidance and recommendations on use of anticoagulants in critically ill patients with COVID-19. © The Author(s) 2022.
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