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Effect of Surface Modification on Viability of L929 Cells on Zirconia Nanocomposite Substrat Publisher



Aivazi M1 ; Fathi M2 ; Nejatidanesh F2 ; Mortazavi V3 ; Beni BH4 ; Matinlinna JP5
Authors
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Authors Affiliations
  1. 1. Biomaterials Research Group, Department of Materials Engineering, Isfahan University of Technology, Isfahan, Iran
  2. 2. Dental Materials Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
  3. 3. Torabinejad Dental Research Center, Department of Operative Dentistry, School of Dentistry, Isfahan University of Medical Sciences, Isfahan, Iran
  4. 4. Department of Anatomical Sciences and Molecular Biology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
  5. 5. Dental Material Science, Head of Unit, Faculty of Dentistry, The University of Hong Kong, 4/FDental Material Science, The Prince Philip Dental Hospital, 34Hospital Road, Sai Ying Pun, Hong Kong

Source: Journal of Lasers in Medical Sciences Published:2018


Abstract

Introduction: Zirconia bioceramic can be considered for metallic replacement in dental implant applications. A proper method of surface modification may promote better osseointegration. Methods: In study evaluated viability of fibroblast cell following surface treatment. Therefore, viability L929 cells were characterized using MTT assay and scanning electron microscopy. Results: The viability assessment determined significant differences A-Y-TZP20 without surface treatment as compared to laser surface treatment (B), laser surface treatment + hydroxyapatite-yttrium stabilized tetragonal zirconia nanocomposite coat (C) and control. This study demonstrated that L929 cells approximately proliferated and spread on A-Y-TZP20 nanocomposite disk in laser surface treatment(B), Laser surface treatment + hydroxiapatite-yttrium stabilized tetragonal zirconia nanocomposite coat (C) groups similar to control group. Conclusion: Laser surface treatment showed positive effect on the viability of L929 cells. © 2018, Laser Application in Medical Sciences Research Center.
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