Surface Microstructure and in Vitro Analysis of Nanostructured Akermanite (Ca2mgsi2o7) Coating on Biodegradable Magnesium Alloy for Biomedical Applications Publisher Pubmed



Razavi M^{1, 3, 4, 5, 6, 7} ; Fathi M^{1, 2} ; Savabi O³ ; Hashemi Beni B⁴ ; Vashaee D⁶ ; Tayebi L^{5, 7}
Source: Colloids and Surfaces B: Biointerfaces Published:2014

Abstract

Magnesium (Mg) alloys, owing to their biodegradability and good mechanical properties, have potential applications as biodegradable orthopedic implants. However, several poor properties including low corrosion resistance, mechanical stability and cytocompatibility have prevented their clinical application, as these properties may result in the sudden failure of the implants during the bone healing. In this research, nanostructured akermanite (Ca2MgSi2O7) powder was coated on the AZ91 Mg alloy through electrophoretic deposition (EPD) assisted micro arc oxidation (MAO) method to modify the properties of the alloy. The surface microstructure of coating, corrosion resistance, mechanical stability and cytocompatibility of the samples were characterized with different techniques including X-ray diffraction (XRD), scanning electron microscopy (SEM), transmission electron microscopy (TEM), electrochemical corrosion test, immersion test, compression test and cell culture test. The results showed that the nanostructured akermanite coating can improve the corrosion resistance, mechanical stability and cytocompatibility of the biodegradable Mg alloy making it a promising material to be used as biodegradable bone implants for orthopedic applications. © 2013.