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In Vitro Analysis of Electrophoretic Deposited Fluoridated Hydroxyapatite Coating on Micro-Arc Oxidized Az91 Magnesium Alloy for Biomaterials Applications Publisher



Razavi M1, 2, 3, 4 ; Fathi M1, 2 ; Savabi O3 ; Vashaee D5 ; Tayebi L4, 6, 7
Authors
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Authors Affiliations
  1. 1. Biomaterials Research Group, Department of Materials Engineering, Isfahan University of Technology, Isfahan, 84156-83111, Iran
  2. 2. Dental Materials Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
  3. 3. Torabinejad Dental Research Center, School of Dentistry, Isfahan University of Medical Sciences, Isfahan, 81746-73461, Iran
  4. 4. School of Materials Science and Engineering, Helmerich Advanced Technology Research Center, Oklahoma State University, Tulsa, 74106, OK, United States
  5. 5. Electrical & Computer Engineering Department, North Carolina State University, Raleigh, 27606, NC, United States
  6. 6. Department of Developmental Sciences, Marquette University School of Dentistry, Milwaukee, 53201, WI, United States
  7. 7. Biomaterials and Advanced Drug Delivery Laboratory, Stanford University, Stanford, CA, United States

Source: Metallurgical and Materials Transactions A: Physical Metallurgy and Materials Science Published:2015


Abstract

Magnesium (Mg) alloys have been recently introduced as a biodegradable implant for orthopedic applications. However, their fast corrosion, low bioactivity, and mechanical integrity have limited their clinical applications. The main aim of this research was to improve such properties of the AZ91 Mg alloy through surface modifications. For this purpose, nanostructured fluoridated hydroxyapatite (FHA) was coated on AZ91 Mg alloy by micro-arc oxidation and electrophoretic deposition method. The coated alloy was characterized through scanning electron microscopy, transmission electron microscopy, X-ray diffraction, in vitro corrosion tests, mechanical tests, and cytocompatibility evaluation. The results confirmed the improvement of the corrosion resistance, in vitro bioactivity, mechanical integrity, and the cytocompatibility of the coated Mg alloy. Therefore, the nanostructured FHA coating can offer a promising way to improve the properties of the Mg alloy for orthopedic applications. © 2015, The Minerals, Metals & Materials Society and ASM International.
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