Isfahan University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
Regeneration or Replacement? a Case Report and Review of Literature Publisher Pubmed



Farhad AR1 ; Shokraneh A2 ; Shekarchizade N3
Authors
Show Affiliations
Authors Affiliations
  1. 1. Torabinejad Dental Research Center and Department of Endodontics, School of Dentistry, Isfahan University of Medical Sciences, Isfahan, Iran
  2. 2. Endodontist, Private Practice, Isfahan, Iran
  3. 3. Department of Endodontics, School of Dentistry, Isfahan University of Medical Sciences, Isfahan, Iran

Source: Dental Traumatology Published:2016


Abstract

Endodontic treatment of immature necrotic teeth is a real challenge. Recently, a biologically based treatment strategy, referred to as regeneration, has been introduced. Tissue regeneration requires the presence of stems cells, a scaffold, and growth factors. Endodontic regeneration may improve the prognosis of immature necrotic teeth by re-establishing the functional pulpal tissue and further development of the root. However, the tissue formed in the pulpal space may not be original pulp tissue, and in some cases, it may result in uncontrolled calcification of the pulp. This study reports a case of successful endodontic regeneration and compares this process with the normal development of the contralateral tooth. Finally, it discusses the nature of the tissue formed during endodontic regeneration. © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.
Related Docs
View other Related Docs
1. Tissue Engineering: Dentin – Pulp Complex Regeneration Approaches (A Review), Tissue and Cell (2017)
2. Outcomes of Revascularization Treatment in Immature Dog's Teeth, Dental Traumatology (2014)
3. Effect of Duration of Root Canal Infection on the Ability of Dentin-Pulp Complex Regeneration of Immature Permanent Teeth: An Animal Study, Journal of Endodontics (2022)
4. Effect of Citric Acid Versus Edta on Radiographic Root Development in Regenerative Endodontic Treatment: An Animal Study, Journal of Endodontics (2022)
5. Nanobiomaterials in Endodontics, Nanobiomaterials in Dentistry: Applications of Nanobiomaterials (2016)
6. A Randomized Controlled Clinical Trial Comparing Clinical and Radiographic Success Rates of Mta and Rhbmp2 in Pulpotomy of Primary Teeth, Frontiers in Dentistry (2024)
7. Improving Pulp Revascularization Outcomes With Buccal Fat Autotransplantation, Journal of Tissue Engineering and Regenerative Medicine (2020)
8. Stem Cells in Dentistry, Sources, and Applications, Dental Hypotheses (2016)
Experts (# of related papers)
View all Related Experts
Abbasali Khademi (14)
Ali Reza Farhad (7)
Other Related Docs
9. Human Pulp Response to Direct Pulp Capping and Miniature Pulpotomy With Mta After Application of Topical Dexamethasone: A Randomized Clinical Trial, Iranian Endodontic Journal (2016)
10. Clinical Management of Dens Invaginatus Type 3: A Case Report, Iranian Endodontic Journal (2011)
11. Antibacterial Effect of Triantibiotic Mixture Versus Calcium Hydroxide in Combination With Active Agents Against Enterococcus Faecalis Biofilm, Dental Materials Journal (2014)
12. Effect of Polyhydroxybutyrate/Chitosan/Bioglass Nanofiber Scaffold on Proliferation and Differentiation of Stem Cells From Human Exfoliated Deciduous Teeth Into Odontoblast-Like Cells, Materials Science and Engineering C (2018)
13. Utilizing Stem Cells in Reconstructive Treatments for Sports Injuries: An Innovative Approach, Tissue and Cell (2023)
14. Sealing Ability of Mta and Cem Cement As Root-End Fillings of Human Teeth in Dry, Saliva or Bloodcontaminated Conditions, Iranian Endodontic Journal (2010)
15. Mechanical or Cold Lateral Compaction: The Incidence of Dentinal Defects, Dental Research Journal (2015)
16. Maxillary Second Molar With Five Root Canals and a Root-Like Enamel Pearl: A Rare Case Report, Iranian Endodontic Journal (2025)
17. Antibacterial Effect of Calcium Hydroxide Combined With Chlorhexidine on Enterococcus Faecalis: A Systematic Review and Meta-Analysis, Journal of Applied Oral Science (2014)
18. Treatment of Strip Perforation Using Root Mta: A Case Report, Iranian Endodontic Journal (2013)
19. Immediate and Delayed Post Space Preparations in Endodontically Treated Teeth: A Scoping Review, BMC Oral Health (2022)
20. Comparative Effectiveness of Hand and Ultrasonic Instrumentations in Root Surface Planing in Vitro, Journal of Clinical Periodontology (2004)
21. The Effect of Time and Storage Environment on Dimensional Changes of Acrylic Resin Post Patterns, Open Dentistry Journal (2015)
22. Nonsurgical Endodontic Treatment of a Maxillary Lateral Incisor With Dens Invaginatus Type Ii: A Case Report, Dental Research Journal (2015)
23. Apical Microleakage Assessment of Calcium Silicate-Based and Resin-Based Sealers by Fluid Filtration Technique, Journal of Dental Materials and Techniques (2022)
24. Esthetic-Based Dental Management of Dentinogenesis Imperfecta in a 2.5-Year-Old Child, Journal of Kerman University of Medical Sciences (2021)
25. Comparison of Clinical and Radiographic Success Between Mta and Biodentine in Pulpotomy of Primary Mandibular Second Molars With Irreversible Pulpitis: A Randomized Double-Blind Clinical Trial, International Journal of Dentistry (2022)
26. Hard Tissue Formation in Pulpotomized Primary Teeth in Dogs With Nanomaterials Mcm-48 and Mcm-48/Hydroxyapatite: An in Vivo Animal Study, BMC Oral Health (2024)
27. Effects of Chitosan As a Novel Obturation Material for Pulpectomized Teeth on Periapical Inflammation, Periodontal Ligament Widening, and Hard Tissue Resorption: A Preliminary Exploratory Study on Dogs, Frontiers in Dentistry (2024)
28. One Visit Endodontic Retreatment With the Aid of Photodynamic Therapy: A Case Report, Journal of International Oral Health (2016)
29. Management of Inflammatory Root Resorption of Maxillary Central Incisors Following Traumatic Avulsion, Case Reports in Dentistry (2021)
30. Comparison of the Microleakage of Mineral Trioxide Aggregate, Calcium-Enriched Mixture Cement, and Biodentine Orthograde Apical Plug, Dental Research Journal (2020)
31. Reconstruction of Natural Smile and Splinting With Natural Tooth Pontic Fiber-Reinforced Composite Bridge, Case Reports in Dentistry (2022)
32. Evaluation of Coronal Microleakage of Mineral Trioxide Aggregate Plug-In Teeth With Short Roots Prepared for Post Placement Using Bacterial Penetration Technique, Indian Journal of Dental Research (2016)
33. Report a Case of Beauty Regeneration in a Child With Premature Tooth Decay, Journal of Babol University of Medical Sciences (2019)
34. Evaluation of Three Restorative Techniques for Primary Anterior Teeth With Extensive Carious Lesions: A 1-Year Clinical Study, Journal of Dentistry for Children (2013)
35. Comparison of Mta, Cem Cement, and Biodentine As Coronal Plug During Internal Bleaching: An in Vitro Study, International Journal of Dentistry (2020)
36. Endodontic Management of a Fused Mandibular Third Molar and Distomolar: A Case Report, Australian Endodontic Journal (2010)
37. Comparative Evaluation of Apical Constriction Position in Incisor and Molar Teeth: An in Vitro Study, European Journal of Dentistry (2018)
38. Effectiveness of Buccal Pouch Grafting in Minimizing Loss of Alveolar Dimension: A Canine Investigation, Dental Research Journal (2019)
39. Cytotoxicity of Two Different Intercanal Medicaments on Human Gingival Fibroblasts-A Laboratory Study, Endodontology (2022)
40. Isolation and Identification of Mesenchymal and Neural Crest Characteristics of Dental Pulp Derived Stem Cells, Koomesh (2015)
41. Pulp Response Following Direct Pulp Capping With Dentin Adhesives and Mineral Trioxide Aggregate; an Animal Study, Iranian Endodontic Journal (2017)
42. Micro-Ct Evaluation of Four Root Canal Obturation Techniques, Scanning (2021)
43. The Effect of Fragaria Vesca Extract on Smear Layer Removal: A Scanning Electron Microscopic Evaluation, Iranian Endodontic Journal (2015)
44. Mapping Global Research in Dental Pulp Regeneration: A 10‑Year Bibliometric Analysis, Dental Research Journal (2024)
45. Prevalence of Chronic Apical Periodontitis Among Patients Referred to the Department of Endodontics at the Kermanshah School of Dentistry (2014–2015); [Wystepowanie Przewleklego Zapalenia Tkanek Okolowierzcholkowych Wsrod Pacjentow Zakladu Endodoncji Szkoly Dentystycznej Kermanshah W Iranie (2014–2015)], Dental and Medical Problems (2016)
46. Histological Characteristics of Dental Pulp in Teeth With Periodontal Problems and Healthy Teeth, Journal of Advanced Periodontology and Implant Dentistry (2023)
47. Compare the Clinical and Radiographic Outcomes of Nonsurgical Endodontic Retreatment and Endodontic Microsurgery: A Systematic Review and Meta-Analysis, International Journal of Pharmaceutical Research (2019)
48. Scanning Electron Microscopic Evaluation of Residual Smear Layer Following Preparation of Curved Root Canals Using Hand Instrumentation or Two Engine-Driven Systems, Iranian Endodontic Journal (2015)
49. The Anterior Palate As a Donor Site in Maxillofacial Bone Grafting: A Quantitative Anatomic Study, Journal of Oral and Maxillofacial Surgery (2005)
50. Health Technology Assessment of Cem Pulpotomy in Permanent Molars With Irreversible Pulpitis, Iranian Endodontic Journal (2013)