Myeloid Sarcoma: Case Series With Unusual Locations



Abedi A¹ ; Namdari N² ; Monabati A¹ ; Safaei A¹ ; Rajabi P³ ; Mokhtari M¹ Show Affiliations
Source: International Journal of Hematology-Oncology and Stem Cell Research Published:2023

Abstract

Myeloid sarcoma (MS) or chloroma is a localized mass composed of blastic cells of granulocytic lineage. It is a subtype of acute myeloid leukemia and usually presents as a complication of acute myeloid leukemia, myeloid dysplastic syndrome, or myeloproliferative disorder. MS occurs in 2.5-9.1% of patients with AML, precedes the clinical disease, coincidence with the onset or at relapse and in rare conditions, it can occur with no evidence of hematologic disorders. Here, we presented seven cases of MS in unusual locations or with rare presentations at presentation or relapse. We concluded that MS should be considered in the differential diagnosis of any high-grade tumor, especially in a patient with previous history of any myeloid neoplasm. © 2023 Tehran University of Medical Sciences.