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Comparison of the Cochlea Dose in Head and Neck Cancer Patients Treated With 3-Dimensional Conformal Radiotherapy and Helical Tomotherapy; [مقایسه ی دوز حلسون گوش در بیماران مبتلا به سرطان سر و گردن تحت درمان با رادیوتراپی سه بعدی انطباقی و توموتراپی حلسونی] Publisher



Rast H1 ; Hemmati S2 ; Shami N3 ; Saeb M1 ; Tavakoli MB1
Authors
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Authors Affiliations
  1. 1. Department of Medical Physics, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
  2. 2. Department of Radio Oncology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
  3. 3. Omid Hospital, Isfahan University of Medical Sciences, Isfahan, Iran

Source: Journal of Isfahan Medical School Published:2023


Abstract

Background: Head and neck cancer (HNC) is among the ten most common cancers worldwide. Due to the complex anatomy of the head and neck, many organs receive radiation during treatment. The aim of this study is to compare the dose received by the cochlea in two different treatment methods, 3D-CRT (Three-Dimensional Conformal Radiotherapy) and HT (Helical Tomotherapy). Methods: The current study is applied and cross-sectional. 28 patients who had nasopharyngeal cancer and were referred to Seyed al-Shohada Hospital (Omid) for treatment between 2020-2022 and were candidates for treatment with one of the 3D-CRT or HT devices; were included in this study. The treatment plan for each patient was simulated in two devices and then study variables such as maximum and average dose and homogeneity and conformity index were investigated. Findings: Comparison of the treatment plans using Helical Tomotherapy (HT) and Three-Dimensional Conformal Radiation Therapy (3D-CRT), Showed that the average dose received by organs at risk, such as the cochlea, was significantly lower in the HT method compared to the 3D-CRT method. This indicating a significant difference between the two treatment methods. Conclusion: Our study on patients with nasopharyngeal cancer revealed that Helical Tomotherapy (HT) treatment led to better target homogeneity and compliance compared to conventional Three-Dimensional Conformal Radiation Therapy (3D-CRT). Additionally, HT was found to reduce the dose delivered to organs at risk (OARs) compared to 3D-CRT. © 2023 Isfahan University of Medical Sciences(IUMS). All rights reserved.
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