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Renoprotective Impact of Angiotensin 1-7: Is It Certain? Publisher



Nematbakhsh M1, 2, 3
Authors
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Authors Affiliations
  1. 1. Water and Electrolytes Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
  2. 2. Department of Physiology, Isfahan University of Medical Sciences, Isfahan, Iran
  3. 3. IsfahanMN Institute of Basic and Applied Sciences Research, Isfahan, Iran

Source: Journal of Nephropathology Published:2019


Abstract

The two important arms of renin angiotensin system (RAS) are angiotensin II (Ang II) and angiotensin1-7 (Ang1-7). Both of these peptides are present in the kidney, while the renal hemodynamic responses to these peptides act differently in kidney circulation. For this short-review, we used a variety of sources including PubMed, Google Scholar, and Scopus. Although in normal physiological condition, Ang1-7 has been known as an inactive agent in the renal system, however in past years many experimental and clinical reports indicated the protective role of Ang1-7 in renal hemodynamics and functions under different circumstances. In the current article, the possible renoprotective role of Ang1-7 was briefly reviewed. © 2019 The Author(s).
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