The Radioprotective Effect of Resveratrol Against Genotoxicity Induced by Γ-Irradiation in Mice Blood Lymphocytes

The Radioprotective Effect of Resveratrol Against Genotoxicity Induced by Γ-Irradiation in Mice Blood Lymphocytes Publisher

Koohian F¹ ; Shanei A¹ ; Shahbazigahrouei D¹ ; Hejazi SH² ; Moradi MT³

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1. Department of Medical Physics, School of Medicine, Isfahan University of Medical Sciences, Hezar Jerib Avenue, Isfahan, Iran
2. Department of Parasitology and Mycology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
3. Medical Plants Research Center, Basic Health Sciences Institute, Shahrekord University of Medical Sciences, Shahrekord, Iran

Source: Dose-Response Published:2017

Abstract

In this study, we evaluated whether the protective potential of resveratrol (RSV; 3,5,4'-trihydroxy-trans-stilbene) against γ-radiation caused damages in peripheral blood lymphocyte of mice. Resveratrol as a polyphenolic compound scavenges free radicals. Various doses of RSV were administered intraperitoneally 2 hours to adult male mice before a single dose of whole-body γ-irradiation (2 Gy). To assess the protective ability of RSV, the alkaline comet assay in blood lymphocyte of mice was performed and the total comet score was evaluated. The results of the alkaline comet assay showed that RSV significantly inhibited radiationinduced DNA damage. We observed that RSV protects blood lymphocyte against radiation-induced damage in mice. © The Author(s) 2017.

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Style	Citing Format
MLA	Koohian F, et al.. "The Radioprotective Effect of Resveratrol Against Genotoxicity Induced by Γ-Irradiation in Mice Blood Lymphocytes." Dose-Response, vol. 15, no. 2, 2017, pp. -.
APA	Koohian F, Shanei A, Shahbazigahrouei D, Hejazi SH, Moradi MT (2017). The Radioprotective Effect of Resveratrol Against Genotoxicity Induced by Γ-Irradiation in Mice Blood Lymphocytes. Dose-Response, 15(2), -.
Chicago	Koohian F, Shanei A, Shahbazigahrouei D, Hejazi SH, Moradi MT. "The Radioprotective Effect of Resveratrol Against Genotoxicity Induced by Γ-Irradiation in Mice Blood Lymphocytes." Dose-Response 15, no. 2 (2017): -.
Harvard	Koohian F et al. (2017) 'The Radioprotective Effect of Resveratrol Against Genotoxicity Induced by Γ-Irradiation in Mice Blood Lymphocytes', Dose-Response, 15(2), pp. -.
Vancouver	Koohian F, Shanei A, Shahbazigahrouei D, Hejazi SH, Moradi MT. The Radioprotective Effect of Resveratrol Against Genotoxicity Induced by Γ-Irradiation in Mice Blood Lymphocytes. Dose-Response. 2017;15(2):-.
BibTex	@article{ author = {Koohian F and Shanei A and Shahbazigahrouei D and Hejazi SH and Moradi MT}, title = {The Radioprotective Effect of Resveratrol Against Genotoxicity Induced by Γ-Irradiation in Mice Blood Lymphocytes}, journal = {Dose-Response}, volume = {15}, number = {2}, pages = {-}, year = {2017} }
RIS	TY - JOUR AU - Koohian F AU - Shanei A AU - Shahbazigahrouei D AU - Hejazi SH AU - Moradi MT TI - The Radioprotective Effect of Resveratrol Against Genotoxicity Induced by Γ-Irradiation in Mice Blood Lymphocytes JO - Dose-Response VL - 15 IS - 2 SP - EP - PY - 2017 ER -

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