Implications of Mirna-590 Dysregulation in Digestive Tract Malignancies: Mechanistic Aspects and Clinical Significance

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Implications of Mirna-590 Dysregulation in Digestive Tract Malignancies: Mechanistic Aspects and Clinical Significance Publisher Pubmed

S Yarahmadi SAHAR ; M Moradi Sarabi MOSTAFA ; Z Abdolvahabi ZOHREH ; Ss Ghorbanhosseini Seyedeh SARA ; E Babaeenezhad ESMAEEL

Source: Molecular Biology Reports Published:2025

Abstract

Digestive tract cancers are a common health concern worldwide. In recent years, dysregulation of miRNA-590 in digestive tract malignancies has been extensively studied. Alterations in its expression are related to clinical outcomes, such as tumor grade, patient prognosis, metastasis, recurrence, response to adjuvant therapy, and overall survival. Therefore, miRNA-590 has the potential to serve as a candidate prognostic and diagnostic biomarker, as well as a therapeutic target. In this study, we focus on the role of miRNA-590 in the biology of digestive tract cancers. It has been shown that miRNA-590 can act as either a tumor suppressor or an oncogene depending on the tumor type, affecting growth, invasion, angiogenesis, and resistance to chemotherapeutic agents. Additionally, we specifically discuss the downstream effects of miRNA-590 and its upstream regulators, as well as its potential as a diagnostic and prognostic marker and promising target for cancer therapy. © 2025 Elsevier B.V., All rights reserved.

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Style	Citing Format
MLA	S Yarahmadi SAHAR, et al.. "Implications of Mirna-590 Dysregulation in Digestive Tract Malignancies: Mechanistic Aspects and Clinical Significance." Molecular Biology Reports, vol. 52, no. 1, 2025, pp. -.
APA	S Yarahmadi SAHAR, M Moradi Sarabi MOSTAFA, Z Abdolvahabi ZOHREH, Ss Ghorbanhosseini Seyedeh SARA, E Babaeenezhad ESMAEEL (2025). Implications of Mirna-590 Dysregulation in Digestive Tract Malignancies: Mechanistic Aspects and Clinical Significance. Molecular Biology Reports, 52(1), -.
Chicago	S Yarahmadi SAHAR, M Moradi Sarabi MOSTAFA, Z Abdolvahabi ZOHREH, Ss Ghorbanhosseini Seyedeh SARA, E Babaeenezhad ESMAEEL. "Implications of Mirna-590 Dysregulation in Digestive Tract Malignancies: Mechanistic Aspects and Clinical Significance." Molecular Biology Reports 52, no. 1 (2025): -.
Harvard	S Yarahmadi SAHAR et al. (2025) 'Implications of Mirna-590 Dysregulation in Digestive Tract Malignancies: Mechanistic Aspects and Clinical Significance', Molecular Biology Reports, 52(1), pp. -.
Vancouver	S Yarahmadi SAHAR, M Moradi Sarabi MOSTAFA, Z Abdolvahabi ZOHREH, Ss Ghorbanhosseini Seyedeh SARA, E Babaeenezhad ESMAEEL. Implications of Mirna-590 Dysregulation in Digestive Tract Malignancies: Mechanistic Aspects and Clinical Significance. Molecular Biology Reports. 2025;52(1):-.
BibTex	@article{ author = {S Yarahmadi SAHAR and M Moradi Sarabi MOSTAFA and Z Abdolvahabi ZOHREH and Ss Ghorbanhosseini Seyedeh SARA and E Babaeenezhad ESMAEEL}, title = {Implications of Mirna-590 Dysregulation in Digestive Tract Malignancies: Mechanistic Aspects and Clinical Significance}, journal = {Molecular Biology Reports}, volume = {52}, number = {1}, pages = {-}, year = {2025} }
RIS	TY - JOUR AU - S Yarahmadi SAHAR AU - M Moradi Sarabi MOSTAFA AU - Z Abdolvahabi ZOHREH AU - Ss Ghorbanhosseini Seyedeh SARA AU - E Babaeenezhad ESMAEEL TI - Implications of Mirna-590 Dysregulation in Digestive Tract Malignancies: Mechanistic Aspects and Clinical Significance JO - Molecular Biology Reports VL - 52 IS - 1 SP - EP - PY - 2025 ER -

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