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Antioxidant Activity of Methanolic Leaf Extract of Moringa Peregrina (Forssk.) Fiori



Dehshahri S1 ; Wink M2 ; Afsharypuor S1 ; Asghari G3 ; Mohagheghzadeh A4
Authors
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Authors Affiliations
  1. 1. Department of Pharmacognosy, School of Pharmacy and Pharmaceutical Sciences, Isfahan University of Medical Sciences, Isfahan, Iran
  2. 2. Institute of Pharmacy and Molecular Biotechnology, Heidelberg University, Germany
  3. 3. Isfahan Pharmaceutical Sciences Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
  4. 4. Department of Pharmacognosy, School of Pharmacy and Pharmaceutical Sciences, Shiraz University of Medical Sciences, Shiraz, Iran

Source: Research in Pharmaceutical Sciences Published:2012

Abstract

Natural antioxidants have an important role in the prevention of many age-related diseases and promotion of health. Among natural antioxidants from plants, flavonoids and other phenolic compounds are potent antioxidants and chelating agents. Moringa peregrina (Forssk.) Fiori (Moringaceae) is a small desert tree distributed from tropical Africa to east India. Moringa tree is also growing in south-east of Iran. The antioxidant activity of M. peregrina methanolic leaf extract on 2,2-diphenyl-1-pycrylhydrazyl and superoxide anion radicals was determined in in vitro experiments. It exhibited the scavenging activity on DPPH and superoxide anion radicals with IC50 of 8.06 ± 0.29 μg/ml and 47.93 ± 1.33 μg/mL, respectively. Moreover, total phenolic content of the leaf extract was determined and using 1HNMR, mass and spectroscopic methods, the structure of the isolated flavonoid glycoside, rutin, as one of the compounds responsible for reported antioxidant activities was identified.
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