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Efficiency of Dimethicone and Symbiotic Approaches in Infantile Colic Management Publisher



Barekatian B1 ; Kelishadi R2 ; Sohrabi F3 ; Yazdi M4
Authors
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Authors Affiliations
  1. 1. Department of Pediatrics, Division of Neonatology, Child Growth and Development Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
  2. 2. Department of Pediatrics, School of Medicine, Child Growth and Development Research Center, Research Institute for Primordial Prevention of Non-communicable Disease, Isfahan University of Medical Sciences, Isfahan, Iran
  3. 3. Department of Pediatrics, Isfahan University of Medical Sciences, Isfahan, Iran
  4. 4. Child Growth and Development Research Center, Research Institute for Primordial Prevention of Non-Communicable Disease, Isfahan University of Medical Sciences, Isfahan, Iran

Source: Iranian Journal of Neonatology Published:2021


Abstract

Background: Infantile colic (IC) (a frequent reason for infantile referral to pediatricians) is a common indiscoverable problem posing concerns for parents. Varieties of theories for the etiology of IC have been raised, and different therapeutic approaches have been recommended in this regard. This study aimed to assess and compare the efficiency of dimethicone versus symbiotic in the treatment of IC. Methods: This randomized clinical trial was conducted on 149 infants with the diagnosis of IC based on the Wessel criteria from 2017 to 2018. The study population was randomly divided into two groups of Dimethicone (n=73) (five drops of dimethicone, three times a day for three weeks) and Symbiotic (n=76) (five daily drops of symbiotic for three weeks). Utilized symbiotic contained fructooligosacharide periodic and probiotic of 109CFU of Bifidobacterium lactis. Duration of an infant crying per day, numbers of crying per day, sleep duration per day, and number of defecation per day were obtained prior to the study and at the end of each week. Results: There was no statistically significant difference between the groups regarding age, gender, and values of breastfeeding (P>0.05). Crying duration, numbers of crying, and sleep duration per day improved significantly in the dimethicone group (P<0.05) within the time as the symbiotic-treated group (P<0.05); however, the comparison of the two groups for IC treatment revealed no statistical differences (P>0.05). Conclusion: The findings of the current study presented that dimethicone and symbiotic could successfully improve IC symptoms regarding crying times, as well as the duration and sleeping time per day. Comparison of these two remedies for IC treatment revealed no significant differences. © 2021 Mashhad University of Medical Sciences. All rights reserved.
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