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Outcomes of a Comprehensive Healthy Lifestyle Program on Cardiometabolic Risk Factors in a Developing Country: The Isfahan Healthy Heart Program Pubmed



Sarrafzadegan N1 ; Kelishadi R1 ; Sadri G2 ; Malekafzali H3 ; Pourmoghaddas M2 ; Heidari K4 ; Shirani S1 ; Bahonar A5 ; Boshtam M1 ; Asgary S6 ; Mohammadifard N1 ; Sadeghi M7 ; Eshrati B8 ; Hadipour E9 Show All Authors
Authors
  1. Sarrafzadegan N1
  2. Kelishadi R1
  3. Sadri G2
  4. Malekafzali H3
  5. Pourmoghaddas M2
  6. Heidari K4
  7. Shirani S1
  8. Bahonar A5
  9. Boshtam M1
  10. Asgary S6
  11. Mohammadifard N1
  12. Sadeghi M7
  13. Eshrati B8
  14. Hadipour E9
  15. Esmaillzadeh A10
  16. Oloughlin JL11
Show Affiliations
Authors Affiliations
  1. 1. Cardiovascular Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
  2. 2. Faculty of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
  3. 3. Department of Biostatistics and Epidemiology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
  4. 4. Isfahan Provincal Health Center, Isfahan University of Medical Sciences, Isfahan, Iran
  5. 5. Hypertension Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
  6. 6. Physiology Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
  7. 7. Cardiac Rehabilitation Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
  8. 8. Arak University of Medical Sciences, Arak, Iran
  9. 9. Najafabad Health Center, Isfahan University of Medical Sciences, Isfahan, Iran
  10. 10. Food Security Research Center, Department of Community Nutrition, School of Nutrition and Food Science, Isfahan University of Medical Sciences, Isfahan, Iran
  11. 11. Department of Social Medicine, University of Montreal, Montreal, Canada

Source: Archives of Iranian Medicine Published:2013


Abstract

Background: This study evaluated the outcome of a comprehensive, community-based healthy lifestyle program on cardiometabolic risk factors. The Isfahan Healthy Heart Program (IHHP) was a comprehensive action-oriented, multi-component intervention with a quasiexperimental design and reference area. Methods: IHHP targeted the population-at-large (n = 2,180,000) in three districts in central Iran. Data from independent sample surveys before (2000-2001) and after (2007) this program were used to compare differences in the intervention area and reference area over time after controlling for age, education level and income. The samples in 2000-2001 and 2007 included 6175 and 4719 participants in intervention area, and 6339 and 4853 in reference area, respectively. Multiple interventional activities were performed based on the four main strategies of healthy nutrition, increased physical activity, tobacco control and coping with stress. Results: The prevalence of abdominal obesity, hypertension, hypercholesterolemia, hypertriglyceridemia and high LDL-C decreased signi cantly in the intervention area versus the reference area in both sexes. However the reduction in overweight and obesity was signicant only in females (P< 0.05 for all). There were no signicant changes in the prevalence of diabetes mellitus. In the intervention area, the prevalence of hypercholesterolemia decreased from 23.5% to 12.5% among females without any changes in females in the reference area (p < 0.0001). In males, hypercholesterolemia decreased signicantly in both intervention area (18.5% to 9.6%) and reference area (14.4% to 9.8%; p = 0.005). Mean triglyceride levels had a signicant decrease in the intervention area and a non-signicant decrease in the reference area (p < 0.0001). Conclusions: A comprehensive healthy lifestyle program comprising preventive and promotional activities that considers both population and high risk approaches can be effective in controlling cardiometabolic risk factors in a middle-income country.
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