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Diagnostic Importance of Performing Myocardial Perfusion Imaging in Covid-19 Patients: A Systematic Review Publisher



Ghorbani M1 ; Esmaeilian S2 ; Rahmanipour E3 ; Sadeghi R4 ; Zahergivar A5 ; Nikkhah R6 ; Askari E4 ; Aali A7 ; Mirzaei M7 ; Kakhki VRD4 ; Daskareh M8
Authors
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Authors Affiliations
  1. 1. Orthopedic Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
  2. 2. Department of Radiology, Shiraz University of Medical Sciences, Shiraz, Iran
  3. 3. Immunology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
  4. 4. Department of Nuclear Medicine, Ghaem Hospital, Mashhad University of Medical Sciences, Mashhad, Iran
  5. 5. Radiology and Imaging Sciences Department, Clinical Center, National Institutes of Health, Bethesda, MD, United States
  6. 6. Isfahan Medical Students Research Committee, Isfahan University of Medical Sciences, Isfahan, Iran
  7. 7. Student Research Committee, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
  8. 8. Department of Radiology, Ziaeian Hospital, Tehran University of Medical Sciences, Tehran, Iran

Source: Iranian Journal of Nuclear Medicine Published:2024


Abstract

Introduction: The coronavirus disease 2019 (COVID-19) pandemic has posed a major challenge to the diagnosis and management of ischemic heart disease (IHD). Myocardial perfusion imaging (MPI) is a non-invasive technique that can assess myocardial ischemia and viability, as well as provide prognostic information for patients with IHD. However, the role of MPI in COVID-19 patients is not well established. Methods: A comprehensive search of PubMed, Embase, Cochrane Library, and Web of Science was conducted to identify relevant studies published until Aprile 24th, 2024. The inclusion criteria were: (1) studies that performed MPI in COVID-19 patients; (2) studies that reported the results of MPI in terms of ischemia, infarction, or perfusion defects; and (3) studies that compared MPI with other diagnostic modalities or clinical outcomes. The quality of the studies was assessed using the QUADAS-2 tool for diagnostic accuracy studies or the ROBIS tool for systematic reviews. A narrative synthesis was performed to summarize the main findings and recommendations. Results: A total of twenty-two studies met the inclusion criteria. The included study information was categorized into the following aspects: Change in the crude number of MPI scans performed, accidental and definite findings in MPI, and the prognostic outcome of COVID patients who underwent MPI. Conclusion: During Covid-19 pandemic, a reduction in the number of MPI studies was seen. Individuals with a history of COVID-19 infection have higher likelihood of developing ischemic heart disease (IHD). SARS-CoV-2 is an independent risk factor for the development of IHD. Copyright © 2024 The Authors.
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