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Mechanical Property of Poly (3-Hydroxybutyrate)/Bioglass Nanocomposite Scaffolds for Bone Tissue Engineering Publisher



Hajiali H1 ; Hosseinalipour M1 ; Karbasi S2 ; Rezaie HR1
Authors
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Authors Affiliations
  1. 1. Biomaterial Group, School of Metallurgy and Materials Engineering, Iran University of Science and Technology (IUST), Tehran, Iran
  2. 2. Medical Physics and Biomedical Engineering Group, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

Source: IFMBE Proceedings Published:2010


Abstract

Because of the excellent osteoconductivity and high bioactivity of bioglass, particularly in the form of nanoparticles, poly (3-hydroxybutyrate)/ bioglass nanocomposite scaffolds were prepared by using salt leaching process. The structures of scaffolds were analyzed by SEM, FTIR and DTA. The scaffolds were prepared in 3 different volume fractions of porosity (70, 80 and 90% wt% of salt particle) and 5 different wt% of bioglass nanoparticles (0, 2.5, 5, 7.5 and 10%). The tensile test results showed that with decreasing volume fraction of porosity and increasing bioglass nanoparticles, Young's modulus and tensile strength of scaffolds were improved significantly. In conclusion, scaffolds were designed with wide range of mechanical property that can be used for bone tissue engineering. © 2010 International Federation for Medical and Biological Engineering.
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