Relationship of Cardiovascular Diseases and Bone Mineral Density in Postmenopausal Women



Dashti G¹ ; Salamat M² ; Sabaghieyazd H³ ; Salamat A⁴
Source: Journal of Isfahan Medical School Published:2014

Abstract

Background: Cardiovascular diseases and osteoporosis are two common chronic conditions particularly in elderly populations, which result in significant morbidity and mortality. Previous studies have shown the relationship of some sorts of heart disease and decrease in bone mineral density (BMD) and presence of osteoporosis. This study aimed to evaluate the relationship of cardiovascular diseases and osteoporosis in postmenopausal women. Methods: 200 patients with a mean age of 66.7 ± 5.8 years (range 52-79 years) were enrolled in this study. Patients were divided in two groups of with and without heart disease according to their medical records. Patients underwent dual-energy x-ray absorptiometry (DXA) measurements at hip and lumbar spines (L2, L3, and L4), greater trochanter, and femur neck. Results were showed as T-score and BMD in g/cm2. The patients were divided into three groups according to T-score (normal, osteopenic, and osteoporotic) after collecting the data, Chi-square (for qualitative variables), t (for quantitative variables), and the Mann-Whitney tests were used for data analysis. Findings: No significant difference was seen between subjects with and without heart disease in mean value of BMD. In addition, there was no statistical significant difference between these two groups in distribution of osteoporotic, osteopenic, and normal density subjects (P > 0.05) in various points of skeleto. Conclusion: In this study, no relationship was observed between cardiovascular disease (as a whole) and BMD and presence of osteoporosis.