The Effect of Quercetin Supplementation on the Components of Metabolic Syndrome in Adults: A Systematic Review and Dose–Response Meta-Analysis of Randomized Controlled Trials Publisher

Summary: Meta-analysis shows quercetin reduces fasting blood glucose and systolic blood pressure in metabolic syndrome. #Quercetin #MetabolicSyndrome

Noshadi N¹ ; Bonyadian A² ; Hojati A³ ; Abbasalizadfarhangi M³ ; Heidari M¹ ; Darzi M⁴ ; Seyedhosseinighaheh H⁵ ; Khajeh M⁶ ; Pourteymour Fard Tabrizi F³ ; Vajdi M⁶ ; Askari G⁷
Source: Journal of Functional Foods Published:2024

Abstract

This systematic review and meta-analysis of randomized controlled trials (RCTs) sought to evaluate the effects of quercetin on the components of (MetS) such as waist circumference (WC), systolic blood pressure (SBP), diastolic blood pressure (DBP), fasting blood glucose (FBG), triglyceride (TG), and high-density lipoprotein cholesterol (HDL-C). A systematic literature search up to December 2023 was completed in Scopus, PubMed, Embase, and Web of Science, to identify eligible RCTs. Altogether, 20 studies with a total sample size of 1,164 subjects were included in the analysis. A pooled analysis showed that quercetin consumption led to a significant reduction in FBG (WMD: −1.03 mg/dL; 95 % CI: −1.87 to −0.19), and SBP (WMD: −1.96 mmHg; 95 % CI: −3.11 to −0.81). However, there were no significant effects on TG, HDL-C, WC, and DBP. It was found that quercetin intake can decrease FBG and SBP significantly without significant effects on other components of MetS. © 2024 The Author(s)