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The Effect of Photobiomodulation Therapy in Common Maxillofacial Injuries: Current Status Publisher Pubmed



Alam M1 ; Karami S2 ; Mohammadikhah M3 ; Badkoobeh A4 ; Golkar M1 ; Abbasi K5 ; Soufdoost RS2 ; Hakim LK6 ; Talebi S7 ; Namanloo RA8 ; Hussain A9 ; Heboyan A10, 11 ; Tebyaniyan H12
Authors
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Authors Affiliations
  1. 1. Department of Oral and Maxillofacial Surgery, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  2. 2. Private Dental Clinic, Tehran, Iran
  3. 3. Department of Oral and Maxillofacial Surgery, School of Dentistry, Alborz University of Medical Sciences, Karaj, Iran
  4. 4. Department of Oral and Maxillofacial Surgery, School of Dentistry, Qom University of Medical Sciences, Qom, Iran
  5. 5. Department of Prosthodontics, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  6. 6. Oral and Maxillofacial Surgeon, Tehran, Iran
  7. 7. Research Committee, School of Dentistry, Isfahan University of Medical Sciences, Isfahan, Iran
  8. 8. Dentistry Department, Bogomolets National Medical University, Kyiv, Ukraine
  9. 9. School of Dentistry, Edmonton Clinic Health Academy, University of Alberta, Edmonton, Canada
  10. 10. Department of Prosthodontics, Faculty of Stomatology, Yerevan State Medical University after Mkhitar Heratsi, Yerevan, Armenia
  11. 11. Department of Research Analytics, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, India
  12. 12. Department of Science and Research, Islimic Azade University, Tehran, Iran

Source: Cell Biochemistry and Function Published:2024


Abstract

The use of photobiomodulation therapy (PBMT) may be used for treating trauma to the maxillofacial region. The effects of PBMT on maxillofacial injuries were discussed in this review article. The electronic databases Pubmed, Scopus, and Web of Science were thoroughly searched. This review included in vitro, in vivo, and clinical studies describing how PBMT can be used in maxillofacial tissue engineering and regenerative medicine. Some studies suggest that PBMT may offer a promising therapy for traumatic maxillofacial injuries because it can stimulate the differentiation and proliferation of various cells, including dental pulp cells and mesenchymal stem cells, enhancing bone regeneration and osseointegration. PBMT reduces pain and swelling after oral surgery and tooth extraction in human and animal models of maxillofacial injuries. Patients with temporomandibular disorders also benefit from PBMT in terms of reduced inflammation and symptoms. PBMT still has some limitations, such as the need for standardizing parameters. PBMT must also be evaluated further in randomized controlled trials in various maxillofacial injuries. As a result, PBMT offers a safe and noninvasive treatment option for patients suffering from traumatic maxillofacial injuries. PBMT still requires further research to establish its efficacy in clinical practice and determine the optimal parameters. © 2024 John Wiley & Sons Ltd.