The Effect of Photobiomodulation Therapy in Common Maxillofacial Injuries: Current Status Publisher Pubmed



Alam M¹ ; Karami S² ; Mohammadikhah M³ ; Badkoobeh A⁴ ; Golkar M¹ ; Abbasi K⁵ ; Soufdoost RS² ; Hakim LK⁶ ; Talebi S⁷ ; Namanloo RA⁸ ; Hussain A⁹ ; Heboyan A^{10, 11} ; Tebyaniyan H¹²
Source: Cell Biochemistry and Function Published:2024

Abstract

The use of photobiomodulation therapy (PBMT) may be used for treating trauma to the maxillofacial region. The effects of PBMT on maxillofacial injuries were discussed in this review article. The electronic databases Pubmed, Scopus, and Web of Science were thoroughly searched. This review included in vitro, in vivo, and clinical studies describing how PBMT can be used in maxillofacial tissue engineering and regenerative medicine. Some studies suggest that PBMT may offer a promising therapy for traumatic maxillofacial injuries because it can stimulate the differentiation and proliferation of various cells, including dental pulp cells and mesenchymal stem cells, enhancing bone regeneration and osseointegration. PBMT reduces pain and swelling after oral surgery and tooth extraction in human and animal models of maxillofacial injuries. Patients with temporomandibular disorders also benefit from PBMT in terms of reduced inflammation and symptoms. PBMT still has some limitations, such as the need for standardizing parameters. PBMT must also be evaluated further in randomized controlled trials in various maxillofacial injuries. As a result, PBMT offers a safe and noninvasive treatment option for patients suffering from traumatic maxillofacial injuries. PBMT still requires further research to establish its efficacy in clinical practice and determine the optimal parameters. © 2024 John Wiley & Sons Ltd.