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Antibiotic Resistance and Nanotechnology: A Narrative Review Publisher Pubmed



Zhu X1 ; Tang Q2 ; Zhou X3 ; Momeni MR4
Authors
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Authors Affiliations
  1. 1. Huaqiao University Hospital, Fujian, Quanzhou, 362021, China
  2. 2. Quanzhou First Hospital, Fujian, Quanzhou, 362000, China
  3. 3. Mudanjiang Medical University, Hei Longjiang, Mu Danjiang, 157012, China
  4. 4. School of Medicine, Tehran University of Medical Sciences, Tehran, Iran

Source: Microbial Pathogenesis Published:2024


Abstract

The rise of antibiotic resistance poses a significant threat to public health worldwide, leading researchers to explore novel solutions to combat this growing problem. Nanotechnology, which involves manipulating materials at the nanoscale, has emerged as a promising avenue for developing novel strategies to combat antibiotic resistance. This cutting-edge technology has gained momentum in the medical field by offering a new approach to combating infectious diseases. Nanomaterial-based therapies hold significant potential in treating difficult bacterial infections by circumventing established drug resistance mechanisms. Moreover, their small size and unique physical properties enable them to effectively target biofilms, which are commonly linked to resistance development. By leveraging these advantages, nanomaterials present a viable solution to enhance the effectiveness of existing antibiotics or even create entirely new antibacterial mechanisms. This review article explores the current landscape of antibiotic resistance and underscores the pivotal role that nanotechnology plays in augmenting the efficacy of traditional antibiotics. Furthermore, it addresses the challenges and opportunities within the realm of nanotechnology for combating antibiotic resistance, while also outlining future research directions in this critical area. Overall, this comprehensive review articulates the potential of nanotechnology in addressing the urgent public health concern of antibiotic resistance, highlighting its transformative capabilities in healthcare. © 2024 Elsevier Ltd
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