Cell Energy: A New Hypothesis in Decoding Cancer Evolution Pubmed



Akbari H^{1, 2} ; Taghizadehhesary F³ ; Heike Y⁴ ; Bahadori M⁵
Source: Archives of Iranian Medicine Published:2019

Abstract

The present study deviates from previous approaches as it focuses on the concept of energy to illuminate cancer-related issues. Energy is a prerequisite for any function; cellular function is no exception, and thus, reduced energy in human cells can impair their performance. This hypothesis provides a novel view of cancer formation. It shows that a normal cell transforms into its cancerous counterpart in response to cellular adenosine triphosphate (ATP) depletion. Moreover, it presents a new definition for the origin of cancer stem cells and how they can regenerate cancer. This article regards a distinct aspect of cancer that helps to differentiate various phases of its progression and shed light on some of the uncharted zones of its pathway for the first time that needs further confirmation by empirical studies. © 2019 The Author(s).