Autophagy in the Regulation of Drug Resistance

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M Hashemi MEHRDAD ; P Rahimzadeh PAYMAN ; Me Vaghar Mohammad ESLAMI ; Ms Bandary Maryam SAHAFI ; Am Jafari Ali MOGHADAS ; R Morovatshoar REZA ; A Aminazad AZARMIDOKHT ; N Zali NEDA ; Hm Arani Hanieh MOTIE ; K Shahpasand KOUROSH

Source: Published:2025

Abstract

Cancer is a complex and chronic condition with a diverse range of causes. The fight against cancer has posed significant challenges for researchers globally in terms of diagnosis and management. Traditional cancer treatments encompass surgery, radiotherapy, and chemotherapy, with the latter often being considered the cornerstone of cancer therapy. However, the prolonged use of chemotherapy can lead to the emergence of drug resistance, a significant hurdle in effective cancer treatment. This resistance arises due to alterations in various biological pathways within the body. Among these, autophagy, a cellular degradation pathway, can play a dual role in cancer. While its regulatory mechanisms can sometimes protect cancer cells and confer drug resistance, its ability to induce cell death can also amplify the effectiveness of chemotherapeutic agents. The intricacies of autophagy’s role in influencing cancer drug resistance are explored in the current discussion. © 2025 Elsevier B.V., All rights reserved.

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Style	Citing Format
MLA	M Hashemi MEHRDAD, et al.. "Autophagy in the Regulation of Drug Resistance." , vol. , no. , 2025, pp. 113-141.
APA	M Hashemi MEHRDAD, P Rahimzadeh PAYMAN, Me Vaghar Mohammad ESLAMI, Ms Bandary Maryam SAHAFI, Am Jafari Ali MOGHADAS, R Morovatshoar REZA, A Aminazad AZARMIDOKHT, N Zali NEDA, Hm Arani Hanieh MOTIE, K Shahpasand KOUROSH (2025). Autophagy in the Regulation of Drug Resistance. , (), 113-141.
Chicago	M Hashemi MEHRDAD, P Rahimzadeh PAYMAN, Me Vaghar Mohammad ESLAMI, Ms Bandary Maryam SAHAFI, Am Jafari Ali MOGHADAS, R Morovatshoar REZA, A Aminazad AZARMIDOKHT, N Zali NEDA, Hm Arani Hanieh MOTIE, K Shahpasand KOUROSH. "Autophagy in the Regulation of Drug Resistance." , no. (2025): 113-141.
Harvard	M Hashemi MEHRDAD et al. (2025) 'Autophagy in the Regulation of Drug Resistance', , (), pp. 113-141.
Vancouver	M Hashemi MEHRDAD, P Rahimzadeh PAYMAN, Me Vaghar Mohammad ESLAMI, Ms Bandary Maryam SAHAFI, Am Jafari Ali MOGHADAS, R Morovatshoar REZA, et al.. Autophagy in the Regulation of Drug Resistance. . 2025;():113-141.
BibTex	@article{ author = {M Hashemi MEHRDAD and P Rahimzadeh PAYMAN and Me Vaghar Mohammad ESLAMI and Ms Bandary Maryam SAHAFI and Am Jafari Ali MOGHADAS and R Morovatshoar REZA and A Aminazad AZARMIDOKHT and N Zali NEDA and Hm Arani Hanieh MOTIE and K Shahpasand KOUROSH}, title = {Autophagy in the Regulation of Drug Resistance}, journal = {}, volume = {}, number = {}, pages = {113-141}, year = {2025} }
RIS	TY - JOUR AU - M Hashemi MEHRDAD AU - P Rahimzadeh PAYMAN AU - Me Vaghar Mohammad ESLAMI AU - Ms Bandary Maryam SAHAFI AU - Am Jafari Ali MOGHADAS AU - R Morovatshoar REZA AU - A Aminazad AZARMIDOKHT AU - N Zali NEDA AU - Hm Arani Hanieh MOTIE AU - K Shahpasand KOUROSH TI - Autophagy in the Regulation of Drug Resistance JO - VL - IS - SP - 113 EP - 141 PY - 2025 ER -

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