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Thromboprophylaxis for Coagulopathy Related to Covid-19 in Pediatrics: A Narrative Review Publisher Pubmed



Sahrai H1 ; Hemmatighavshough M1 ; Shahrabi M2 ; Jafarirouhi AH3 ; Solduzian M4
Authors
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Authors Affiliations
  1. 1. Student research committee, Tabriz University of Medical Sciences, Tabriz, Iran
  2. 2. Department of Clinical Pharmacy, School of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
  3. 3. Tuberculosis and Lung Disease Research Center, Tabriz University of medical Sciences, Tabriz, Iran
  4. 4. Department of Clinical Pharmacy, Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran

Source: Pediatric Drugs Published:2023


Abstract

In addition to harming the respiratory system, COVID-19 can affect multiple organs. Children may develop a specific complication of COVID-19 called multisystem inflammatory syndrome in children (MIS-C) which could influence the vascular system of children and cause multiple coagulopathies in the body. Information on the use of thromboprophylaxis in this condition was collected via the review of various articles. In general, different factors in immune system responses can trigger the initiation of thrombotic events. Studies have shown that starting anticoagulant prophylaxis, which contributes to decreased thrombotic events, is dependent on the patient's condition and D-dimer levels. However, further studies on pediatric populations are needed to establish the role of anticoagulants in children with this condition. © 2023, The Author(s), under exclusive licence to Springer Nature Switzerland AG.