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Increased Intracranial Pressure on a Patient With Neuromyelitis Optica Spectrum Disorder Publisher



Forouzannia SM1 ; Yarahmadi P1 ; Alirezaei M1 ; Rezaeimanesh N1 ; Moghadasi AN1
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Authors Affiliations
  1. 1. Multiple Sclerosis Research Center, Neuroscience Institute, Tehran University of Medical Sciences, Tehran, Iran

Source: Caspian Journal of Internal Medicine Published:2021


Abstract

Background: Neuromyelitis optica spectrum disorder (NMOSD) is an autoimmune astrocytopathic disease affecting central nervous system (CNS). CSF pressure in these patients is usually normal. Case Presentation: A 30-year-old woman was admitted with complaints of headache and lower limbs paresis. Lumbar puncture (LP) and magnetic resonance imaging were performed for the patient. Opening pressure was 42 cm H2O in the first LP. According to the clinical evidences, imaging, and the patient's positive aquaporin-4 antibody, the diagnosis of NMOSD was established. Conclusion: High intracranial pressure headache; however rare, may be the first sign of the onset of the acute exacerbation phase of NMOSD. © The Author(s).
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