Real-Time Diagnosis of Reactive Oxygen Species (Ros) in Fresh Sputum by Electrochemical Tracing; Correlation Between Covid-19 and Viral-Induced Ros in Lung/Respiratory Epithelium During This Pandemic

Real-Time Diagnosis of Reactive Oxygen Species (Ros) in Fresh Sputum by Electrochemical Tracing; Correlation Between Covid-19 and Viral-Induced Ros in Lung/Respiratory Epithelium During This Pandemic Publisher Pubmed

Miripour ZS¹ ; Sarramiforooshani R² ; Sanati H² ; Makarem J³ ; Taheri MS⁴ ; Shojaeian F⁵ ; Eskafi AH⁶ ; Abbasvandi F² ; Namdar N¹ ; Ghafari H¹ ; Aghaee P¹ ; Zandi A¹ ; Faramarzpour M¹ ; Hoseinyazdi M⁷ Show All Authors

Miripour ZS¹
Sarramiforooshani R²
Sanati H²
Makarem J³
Taheri MS⁴
Shojaeian F⁵
Eskafi AH⁶
Abbasvandi F²
Namdar N¹
Ghafari H¹
Aghaee P¹
Zandi A¹
Faramarzpour M¹
Hoseinyazdi M⁷
Tayebi M²
Abdolahad M¹

Show Affiliations

1. Nano Electronic Center of Excellence, Nano Bio Electronic Devices Lab, School of Electrical and Computer Engineering, College of Engineering, University of Tehran, P.O. Box: 14395/515, Tehran, Iran
2. ATMP Department, Breast Cancer Research Center, Motamed Cancer Institute, ACECR, P.O. BOX: 15179/64311, Tehran, Iran
3. Department of Anesthesia, Imam Khomeini Hospital, Tehran University of Medical Sciences, P.O. BOX: 1417653761, Tehran, Iran
4. Department of Radiology, Shohada Hospital, Shahid Beheshti University of Medical Sciences, P.O. BOX: 1445613131, Tehran, Iran
5. School of Medicine, Shahid Beheshti University of Medical Sciences, P.O. BOX: 1985717443, Tehran, Iran
6. Biotechnology Research Center, Biotechnology Department, Venom & Biotherapeutics Molecules Lab., Pasteur Institute of Iran, P.O. BOX: 131694-3551, Tehran, Iran
7. School of Medicine, Shiraz University of Medical Sciences, P.O. BOX: 71348-14336, Shiraz, Iran

Source: Biosensors and Bioelectronics Published:2020

Abstract

COVID-19 is the shocking viral pandemics of this year which affected the health, economy, communications, and all aspects of social activities all over the world. Early diagnosis of this viral disease is very important since it can prevent lots of mortalities and care consumption. The functional similarities between COVID-19 and COVID-2 in inducing acute respiratory syndrome lightened our mind to find a diagnostic mechanism based on early traces of mitochondrial ROS overproduction as lung cells’ dysfunctions induced by the virus. We designed a simple electrochemical sensor to selectively detect the intensity of ROS in the sputum sample (with a volume of less than 500 μl). Comparing the results of the sensor with clinical diagnostics of more than 140 normal and involved cases resulted in a response calibration with accuracy and sensitivity both 97%. Testing the sensor in more than 4 hospitals shed promising lights in ROS based real-time tracing of COVID-19 from the sputum sample. © 2020 Elsevier B.V.

Related Docs

View other Related Docs

1. How Cytosolic Compartments Play Safeguard Functions Against Neuroinflammation and Cell Death in Cerebral Ischemia, Metabolic Brain Disease (2021)

2. Non-Coding Rnas Affecting Nlrp3 Inflammasome Pathway in Diabetic Cardiomyopathy: A Comprehensive Review of Potential Therapeutic Options, Journal of Translational Medicine (2025)

3. All-Trans Retinoic Acid–Preconditioned Mesenchymal Stem Cells Improve Motor Function and Alleviate Tissue Damage After Spinal Cord Injury by Inhibition of Hmgb1/Nf-Κb/Nlrp3 Pathway Through Autophagy Activation, Journal of Molecular Neuroscience (2022)

4. Infection and Immunity, Clinical Immunology (2022)

5. Nlrp Inflammasome As a Key Role Player in the Pathogenesis of Environmental Toxicants, Life Sciences (2019)

6. The Nlrp3 Inflammasome: A Therapeutic Target for Inflammation-Associated Cancers, Expert Review of Clinical Immunology (2020)

7. Crosstalk Between Autophagy and Insulin Resistance: Evidence From Different Tissues, European Journal of Medical Research (2023)

8. Mechanisms of Inflammatory Responses to Radiation and Normal Tissues Toxicity: Clinical Implications, International Journal of Radiation Biology (2018)

Experts (# of related papers)

View all Related Experts

Nima Rezaei (4)

Gholamreza Hassanzadeh (1)

Style	Citing Format
MLA	Miripour ZS, et al.. "Real-Time Diagnosis of Reactive Oxygen Species (Ros) in Fresh Sputum by Electrochemical Tracing; Correlation Between Covid-19 and Viral-Induced Ros in Lung/Respiratory Epithelium During This Pandemic." Biosensors and Bioelectronics, vol. 165, no. , 2020, pp. -.
APA	Miripour ZS, Sarramiforooshani R, Sanati H, Makarem J, Taheri MS, Shojaeian F, Eskafi AH, Abbasvandi F, Namdar N, Ghafari H, Aghaee P, Zandi A, Faramarzpour M, Hoseinyazdi M, Tayebi M, Abdolahad M (2020). Real-Time Diagnosis of Reactive Oxygen Species (Ros) in Fresh Sputum by Electrochemical Tracing; Correlation Between Covid-19 and Viral-Induced Ros in Lung/Respiratory Epithelium During This Pandemic. Biosensors and Bioelectronics, 165(), -.
Chicago	Miripour ZS, Sarramiforooshani R, Sanati H, Makarem J, Taheri MS, Shojaeian F, Eskafi AH, et al.. "Real-Time Diagnosis of Reactive Oxygen Species (Ros) in Fresh Sputum by Electrochemical Tracing; Correlation Between Covid-19 and Viral-Induced Ros in Lung/Respiratory Epithelium During This Pandemic." Biosensors and Bioelectronics 165, no. (2020): -.
Harvard	Miripour ZS et al. (2020) 'Real-Time Diagnosis of Reactive Oxygen Species (Ros) in Fresh Sputum by Electrochemical Tracing; Correlation Between Covid-19 and Viral-Induced Ros in Lung/Respiratory Epithelium During This Pandemic', Biosensors and Bioelectronics, 165(), pp. -.
Vancouver	Miripour ZS, Sarramiforooshani R, Sanati H, Makarem J, Taheri MS, Shojaeian F, et al.. Real-Time Diagnosis of Reactive Oxygen Species (Ros) in Fresh Sputum by Electrochemical Tracing; Correlation Between Covid-19 and Viral-Induced Ros in Lung/Respiratory Epithelium During This Pandemic. Biosensors and Bioelectronics. 2020;165():-.
BibTex	@article{ author = {Miripour ZS and Sarramiforooshani R and Sanati H and Makarem J and Taheri MS and Shojaeian F and Eskafi AH and Abbasvandi F and Namdar N and Ghafari H and Aghaee P and Zandi A and Faramarzpour M and Hoseinyazdi M and Tayebi M and Abdolahad M}, title = {Real-Time Diagnosis of Reactive Oxygen Species (Ros) in Fresh Sputum by Electrochemical Tracing; Correlation Between Covid-19 and Viral-Induced Ros in Lung/Respiratory Epithelium During This Pandemic}, journal = {Biosensors and Bioelectronics}, volume = {165}, number = {}, pages = {-}, year = {2020} }
RIS	TY - JOUR AU - Miripour ZS AU - Sarramiforooshani R AU - Sanati H AU - Makarem J AU - Taheri MS AU - Shojaeian F AU - Eskafi AH AU - Abbasvandi F AU - Namdar N AU - Ghafari H AU - Aghaee P AU - Zandi A AU - Faramarzpour M AU - Hoseinyazdi M AU - Tayebi M AU - Abdolahad M TI - Real-Time Diagnosis of Reactive Oxygen Species (Ros) in Fresh Sputum by Electrochemical Tracing; Correlation Between Covid-19 and Viral-Induced Ros in Lung/Respiratory Epithelium During This Pandemic JO - Biosensors and Bioelectronics VL - 165 IS - SP - EP - PY - 2020 ER -

Science Communicator Platform

Authors

Authors Affiliations

Abstract