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New Finding in Vernal Keratoconjunctivitis: Splendore-Hoeppli Phenomenon Publisher Pubmed



Soleimani M1 ; Tabatabaei SA1 ; Mirshahi R1 ; Nozarian Z1 ; Behrbouz MJ1
Authors
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Authors Affiliations
  1. 1. Eye Research Center, Ocular Trauma and Emergency Unit, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, 1336616351, Iran

Source: Cornea Published:2016


Abstract

Purpose: To report 2 cases of Splendore-Hoeppli phenomenon, a rare histopathologic observation, as a late clinical finding in vernal keratoconjunctivitis (VKC). Methods: We report the cases of 2 young women with subconjunctival nodules as a manifestation of Splendore-Hoeppli phenomenon with a history of severe VKC. Results: After eliminating other conditions causing such a reaction, both patients were treated using frequent topical corticosteroid, plus topical cyclosporine 2% in one of patient. Complete resolution was observed in both patients. Conclusions: The Splendore-Hoeppli phenomenon could be a part of VKC manifestations. © 2016 Wolters Kluwer Health, Inc. All rights reserved.