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Evaluation of the Safety of Ovarian Preservation at Early Stage of Endometrial Cancer in Premenopausal Women Publisher



Shirali E1 ; Gilani MM1 ; Yarandi F1 ; Hemmatian O1 ; Ahmadzadeh A2 ; Kazemi Z3 ; Ghaemi M4
Authors
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Authors Affiliations
  1. 1. Department of Gynecologic Oncology, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Department of Gynecologic Oncology, Ahvaz University of Medical Sciences, Ahvaz, Iran
  3. 3. Department of Gynecologic Oncology, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  4. 4. Valie-Asr Reproductive Health Research Center (VRHRC), Tehran University of Medical Sciences, Tehran, Iran

Source: Journal of Iranian Medical Council Published:2020


Abstract

Background: Endometrial cancer usually occurs at postmenopause stage of life but its incidence in younger patients is increasing in the last decades. The objective of the study was to evaluate the ovarian preservation in the early stage of endometrial cancer. Methods: In this cross-sectional study, 174 patients with endometrial cancer who underwent Total Abdominal Hysterectomy (TAH) and Bilateral Salpingo-oophorectomy in 5 years were included. Results: The results showed that 51.1% of the patients were at stage IA, 28.7% at stage IB, 6.9% at stage II, 11.5% at stage III and 1.7% at stage IV of endometrial cancer when they underwent surgery. One patient (1.12%) at stage IA of endometrial cancer, one patient (2%) at stage IB and one patient (8.3%) at stage II had micrometastasis in ovaries, and 8 patients (40%) at stage III and 2 patients (66.6%) at stage IV had micrometastasis and co-existing tumor. Conclusion: In conclusion, findings revealed the high safety of ovarian preservation in endometrial cancer at earlier stages of the endometrial cancer with low risk of ovarian involvement. © 2020, Journal of Iranian Medical Council.
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