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Neutrophil to Lymphocyte Ratio in Epilepsy: A Systematic Review Publisher Pubmed



Hosseini S1 ; Mofrad AME2 ; Mokarian P3 ; Nourigheimasi S4 ; Azarhomayoun A5 ; Khanzadeh S6 ; Habibzadeh S7 ; Ghaedi A8
Authors
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Authors Affiliations
  1. 1. Neurosciences Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
  2. 2. Ahvaz Jundishapur University of Medical Sciences, Iran
  3. 3. Fasa University of Medical Sciences, Fasa, Iran
  4. 4. School of Medicine, Arak University of Medical Sciences, Arak, Iran
  5. 5. Sina Trauma and Surgery Research Center, Tehran University of Medical Sciences, Tehran, Iran
  6. 6. Student Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran
  7. 7. Clinical Research Development Unit of Children Hospital Tabriz University of Medical Science, Tabriz, Iran
  8. 8. Student Research Committee, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran

Source: Mediators of Inflammation Published:2022


Abstract

This study was conducted to summarize the results of studies investigating the role of neutrophil to lymphocyte ratio (NLR) in epilepsy. The search was conducted on PubMed, Scopus, and Web of Science up to December 25, 2021. Finally, a total of seven studies were included in the review. The NLR in patients who were in the acute phase was higher than that of healthy. NLR in the patients who were in either acute or subacute phase was higher than in healthy controls. A significant difference in NLR levels between the acute and subacute phases was also noted. Epilepsy is one of the most important neurological diseases in the world, and millions of people around the world suffer from it, and a cheap and fast biomarker is needed for it. The interesting thing is that inflammation plays a role in epilepsy, and elevated NLR value can be a good biomarker of inflammation and, as a result, for epilepsy. © 2022 Samaneh Hosseini et al.
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