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In Vitro Cytotoxicity of Gd2o3 Nanoparticles With Diethylene Glycol Polymer in Human Melanoma Cell Line



Behrouzkia Z1 ; Agdam RZ2 ; Riyahialam N3 ; Refahi S4
Authors

Source: Research Journal of Pharmaceutical# Biological and Chemical Sciences Published:2015

Abstract

Nanoparticles are exceptional in that their physical and chemical properties enable many promising medicinal applications. It is widely accepted that nanoparticles should be thoroughly tested for health hazards or nanotoxicity. The purpose of this study was to assess in vitro cytotoxicity of Gadolinium oxide nanoparticles in Human melanoma Cell Line. The effects of magnetic nanoparticles on this cell were evaluated by light microscopy and by standard cytotoxicity assays. Our results demonstrate a concentration-dependent toxicity for all types of particles tested. Our results suggest that this cell lines provides valuable models to assess the cytotoxicity of nanoparticles in human melanoma Cell Line in vitro.
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